Domains within Streptomyces noursei ATCC 11455 protein A0A1B2GJH2_STRNR (A0A1B2GJH2)
Modular polyketide synthase
Alternative representations: 1 /
| Protein length | 2066 aa |
|---|---|
| Source database | UniProt |
| Identifiers | Q9L4X1_STRNR, Q9L4X1, A0A1B2GJH2_STRNR, A0A1B2GJH2 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
A0A1B2GJH2_STRNR is shown as 
ANZ14080.1 in the network
Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.
The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein A0A1B2GJH2_STRNR is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map01052 | Type I polyketide structures | iPath3 |
| map01110 | Biosynthesis of secondary metabolites |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K00665 | FASN | fatty acid synthase, animal type [EC:2.3.1.85] | iPath3 |
| K02364 | entF | L-serine---[L-seryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.72] | iPath3 |
| K15894 | pseB, wbjB | UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-] | |
| K19205 | pimS3 | pimaricinolide synthase PimS3 | |
| K12444 | ppsE | phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292] | |
| K16435 | evaA, eryBVI, tylCVI, tylX3, staJ | dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase [EC:4.2.1.159] | iPath3 |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 316284.SNOUR_03800 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG3321 | All organisms (root) | fatty acid synthase, animal type [EC:2.3.1.85],chalcone synthase [EC:2.3.1.74],phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292] |
| LCOG1086 | All organisms (root) | UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-],UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135],undecaprenyl-phosphate glucose phosphotransferase [EC:2.7.8.31] |
| LCOG3208 | All organisms (root) | dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase [EC:4.2.1.159],pyochelin biosynthesis protein PchC,pimeloyl-[acyl-carrier protein] methyl ester esterase [EC:3.1.1.85] |
| COG3321 | Bacteria (superkingdom) | phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292],polyketide synthase 13,phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase C [EC:2.3.1.292] |
| COG1086 | Bacteria (superkingdom) | UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-],UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135],undecaprenyl-phosphate glucose phosphotransferase [EC:2.7.8.31] |
| COG3208 | Bacteria (superkingdom) | dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase [EC:4.2.1.159],pyochelin biosynthesis protein PchC,yersiniabactin synthetase, thioesterase component |
| 68WH6 | Actinobacteria (phylum) | L-serine---[L-seryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.72],polyketide synthase 7,phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase B [EC:2.3.1.292] |
| FBI9D | Actinomycetia (class) | L-serine---[L-seryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.72],polyketide synthase 7,phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase B [EC:2.3.1.292] |
| BBHEW | Streptomycetaceae (family) | polyene macrolide polyketide synthase,pimaricinolide synthase PimS3,pimaricinolide synthase PimS4 |
| CISG3 | Streptomyces (genus) | polyene macrolide polyketide synthase,pimaricinolide synthase PimS3,pimaricinolide synthase PimS4 |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.