Domains within Oryctolagus cuniculus protein Q9MYW4_RABIT (Q9MYW4)

BCL2 like 1

Alternative representations: 1 /

Protein length233 aa
Source databaseUniProt
Identifiers Q9MYW4_RABIT, Q9MYW4, ENSOCUP00000002775.2, ENSOCUP00000002775
Source gene ENSOCUG00000003201

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

Q9MYW4_RABIT is shown as BCL2L1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for BCL2L1

Protein Q9MYW4_RABIT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04210Apoptosis
map04215Apoptosis - multiple species
map05225Hepatocellular carcinoma
map05014Amyotrophic lateral sclerosis

KEGG orthologous groups

KONameDescription
K04570BCL2L1, bcl-xLBcl-2-like 1 (apoptosis regulator Bcl-X)
K02561BOKBcl-2-related ovarian killer protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9986.ENSOCUP00000002775 in eggNOG.

OGTaxonomic classDescription
LKOG4728All organisms (root)Bcl-2-related ovarian killer protein,apoptosis regulator BAX,Bcl-2-like 1 (apoptosis regulator Bcl-X)
KOG4728Eukaryota (superkingdom)Bcl-2-related ovarian killer protein,apoptosis regulator BAX,Bcl-2-like 1 (apoptosis regulator Bcl-X)
HUQEJMetazoa (kingdom)Bcl-2-like 1 (apoptosis regulator Bcl-X),apoptosis regulator BCL-W,apoptosis regulator Bcl-2
93PQKChordata (phylum)Bcl-2-like 1 (apoptosis regulator Bcl-X)
5QFP9Sarcopterygii (superclass)Bcl-2-like 1 (apoptosis regulator Bcl-X)
8YU1CMammalia (class)Bcl-2-like 1 (apoptosis regulator Bcl-X)
4RS05Euarchontoglires (superorder)Bcl-2-like 1 (apoptosis regulator Bcl-X)
9FY7NVertebrata (clade)Bcl-2-like 1 (apoptosis regulator Bcl-X)
7IC3XOpisthokonta (clade)Bcl-2-like 1 (apoptosis regulator Bcl-X),apoptosis regulator BCL-W,apoptosis regulator Bcl-2
H54XZBilateria (clade)Bcl-2-like 1 (apoptosis regulator Bcl-X),apoptosis regulator BCL-W,apoptosis regulator Bcl-2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: