Domains within Drosophila melanogaster protein CEG1A_DROME (Q9NGC3)

Centaurin-gamma-1A

Alternative representations: 1 /

Protein length995 aa
Source databaseUniProt
Identifiers CEG1A_DROME, Q9NGC3, FBPP0080123, B7FNK5, I0C0M3, Q6IDF7, Q86P12, Q8MR30, Q95SF3, Q9NKE5, Q9VJV4, Q9VJV5, Q9VJV7, Q9NGC3-3
Source gene FBgn0028509
Alternative splicing CEG1A_DROME, FBpp0080125, Q9NGC3-2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

CEG1A_DROME is shown as CenG1A in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CenG1A

Protein CEG1A_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04144Endocytosis

KEGG orthologous groups

KONameDescription
K12491AGAPArf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 26 PTMs annotated in this protein:

PTMCount
Phosphorylation22
Ubiquitination3
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein cenG1A.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0080123 in eggNOG.

OGTaxonomic classDescription
FE4ADmelanogaster subgroup (species subgroup)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
FUZ92melanogaster group (species group)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
LKOG0705All organisms (root)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11,Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2,cyclin-dependent kinase 4 [EC:2.7.11.22]
EINCQEndopterygota (cohort)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
KOG0705Eukaryota (superkingdom)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11,Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2,cyclin-dependent kinase 4 [EC:2.7.11.22]
HTY5SMetazoa (kingdom)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11,Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2,cyclin-dependent kinase 4 [EC:2.7.11.22]
HI51AArthropoda (phylum)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
85I87Hexapoda (subphylum)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
AGKFINeoptera (infraclass)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
ANG24Diptera (order)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
H3EPABilateria (clade)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11,Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2,cyclin-dependent kinase 4 [EC:2.7.11.22]
7HCUQOpisthokonta (clade)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11,Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2,cyclin-dependent kinase 4 [EC:2.7.11.22]
EH13QDrosophila (genus)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11
50KRFSophophora (subgenus)Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3/4/5/6/9/11

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: