Domains within Homo sapiens protein IL26_HUMAN (Q9NPH9)

Interleukin-26

Alternative representations: 1 /

Protein length171 aa
Source databaseUniProt
Identifiers IL26_HUMAN, Q9NPH9, ENSP00000229134.4, ENSP00000229134, H2Q6F4_PANTR, H2Q6F4, G3R6F4_GORGO, G3R6F4
Source gene ENSG00000111536

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

IL26_HUMAN is shown as IL26 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for IL26

Protein IL26_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04060Cytokine-cytokine receptor interaction

KEGG orthologous groups

KONameDescription
K05446IL26interleukin 26

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSPTRG00000005194.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000229134 in eggNOG.

OGTaxonomic classDescription
77T75All organisms (root)interleukin 26
5I53SEukaryota (superkingdom)interleukin 26
HT3YYMetazoa (kingdom)interleukin 26
94UCDChordata (phylum)interleukin 26
5QQS7Sarcopterygii (superclass)interleukin 26
8YXUTMammalia (class)interleukin 26
4RPZ4Euarchontoglires (superorder)interleukin 26
4ZM73Primates (order)interleukin 26
988Z8Haplorrhini (suborder)interleukin 26
BVDYTSimiiformes (infraorder)interleukin 26
9F1DTCatarrhini (parvorder)interleukin 26
H58K5Bilateria (clade)interleukin 26
9G5WGVertebrata (clade)interleukin 26
7K58AOpisthokonta (clade)interleukin 26
FXDNYHominoidea (superfamily)interleukin 26
5N7FZHominidae (family)interleukin 26
5Y24CHomininae (subfamily)interleukin 26

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: