Domains within Homo sapiens protein SNTG1_HUMAN (Q9NSN8)

Gamma-1-syntrophin

Alternative representations: 1 /

Protein length517 aa
Source databaseUniProt
Identifiers SNTG1_HUMAN, Q9NSN8, ENSP00000429276.1, ENSP00000429276, ENSP00000493900.1, ENSP00000493900, ENSP00000429842.1, ENSP00000429842, Q2M3Q0, Q9NY98, A0A024R7Y0_HUMAN, A0A024R7Y0, E5RIN0_HUMAN, E5RIN0, A0A2J8UMZ8_PONAB, A0A2J8UMZ8, A0A2J8L4R4_PANTR, A0A2J8L4R4
Source gene ENSG00000147481
Alternative splicing SNTG1_HUMAN, ENSP00000494985.1, UPI0005D003E3, ENSP00000494759.1, ENSP00000493658.1, ENSP00000495470.1, ENSP00000496147.1, ENSP00000495100.1, ENSP00000495550.1, ENSP00000496525.1, ENSP00000496116.1, Q9NSN8-2, ENSP00000494442.1, ENSP00000429363.1, ENSP00000496330.1, UPI0000210689, E5RHN6_HUMAN, H0YC21_HUMAN, ENSP00000494958.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

SNTG1_HUMAN is shown as SNTG1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SNTG1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 5 PTMs annotated in this protein:

PTMCount
Acetylation3
Phosphorylation1
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein SNTG1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000493900 in eggNOG.

OGTaxonomic classDescription
LKOG3549All organisms (root)gamma-syntrophin
KOG3549Eukaryota (superkingdom)gamma-syntrophin
HUXIVMetazoa (kingdom)gamma-syntrophin
94WGZChordata (phylum)gamma-syntrophin
5QZCZSarcopterygii (superclass)gamma-syntrophin
8Z92MMammalia (class)gamma-syntrophin
4RPVZEuarchontoglires (superorder)gamma-syntrophin
4ZNP2Primates (order)gamma-syntrophin
987AMHaplorrhini (suborder)gamma-syntrophin
BVHHASimiiformes (infraorder)gamma-syntrophin
9EREZCatarrhini (parvorder)gamma-syntrophin
7GGSQOpisthokonta (clade)gamma-syntrophin
9GEU0Vertebrata (clade)gamma-syntrophin
H4FICBilateria (clade)gamma-syntrophin
FWYDNHominoidea (superfamily)gamma-syntrophin
5N7VDHominidae (family)gamma-syntrophin
5XYZYHomininae (subfamily)gamma-syntrophin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: