Domains within Homo sapiens protein DZAN1_HUMAN (Q9NVP4)

Double zinc ribbon and ankyrin repeat-containing protein 1

Alternative representations: 1 /

Protein length752 aa
Source databaseUniProt
Identifiers Q9NVP4, DZAN1_HUMAN, ENSP00000351734.6, ENSP00000351734, ENSP00000262547.5, ENSP00000262547, B7ZLZ4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442
Source gene ENSG00000089091
Alternative splicing A0A087WVH4_HUMAN, A0A087WTH2_HUMAN, A0A0A0MRE2_HUMAN, DZAN1_HUMAN, V9GY46_HUMAN, Q9NVP4-3, ENSP00000484666.1, C9J2A8_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

DZAN1_HUMAN is shown as DZANK1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for DZANK1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein C20orf12.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000262547 in eggNOG.

OGTaxonomic classDescription
6WT1UAll organisms (root)DZR,Fn3_assoc,Ank_2
5FR8DEukaryota (superkingdom)DZR,Fn3_assoc,Ank_2
HTGH9Metazoa (kingdom)DZR,Fn3_assoc,Ank_2
93SNEChordata (phylum)DZR,Fn3_assoc,Ank_2
5QG1GSarcopterygii (superclass)DZR,Fn3_assoc,Ank_2
8Z9ZZMammalia (class)DZR,Fn3_assoc,Ank_2
4RKGUEuarchontoglires (superorder)Fn3_assoc,DZR,Ank_2
505DCPrimates (order)DZR,Fn3_assoc,Ank_2
989QEHaplorrhini (suborder)Fn3_assoc,DZR,Ank_2
BV0R6Simiiformes (infraorder)Fn3_assoc,DZR,Ank_2
9ESEACatarrhini (parvorder)Fn3_assoc,DZR,Ank_2
9G5N1Vertebrata (clade)DZR,Fn3_assoc,Ank_2
7K683Opisthokonta (clade)DZR,Fn3_assoc,Ank_2
H5PBZBilateria (clade)DZR,Fn3_assoc,Ank_2
FXCR9Hominoidea (superfamily)Fn3_assoc,DZR,Ank_2
5MZ8NHominidae (family)Fn3_assoc,DZR,Ank_2
5Y6CCHomininae (subfamily)Fn3_assoc,DZR

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: