Domains within Homo sapiens protein ANR10_HUMAN (Q9NXR5)

Ankyrin repeat domain-containing protein 10

Alternative representations: 1 /

Protein length420 aa
Source databaseUniProt
Identifiers ANR10_HUMAN, Q9NXR5, ENSP00000267339.2, ENSP00000267339, Q5VW12, Q9BV12, A0A024RE01_HUMAN, A0A024RE01
Source gene ENSG00000088448
Alternative splicing ANR10_HUMAN, S4R3R2_HUMAN, ENSP00000312534.4, Q8IUW1_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ANR10_HUMAN is shown as ANKRD10 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ANKRD10

Protein ANR10_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05166Human T-cell leukemia virus 1 infection

KEGG orthologous groups

KONameDescription
K10999CESAcellulose synthase A [EC:2.4.1.12]
K06867K06867uncharacterized protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 1 PTMs annotated in this protein:

PTMCount
Phosphorylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ANKRD10.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000267339 in eggNOG.

OGTaxonomic classDescription
LCOG0666All organisms (root)uncharacterized protein,Mce-associated membrane protein,cellulose synthase A [EC:2.4.1.12]
KOG0504Eukaryota (superkingdom)cellulose synthase A [EC:2.4.1.12],beta-mannan synthase [EC:2.4.1.32],uncharacterized protein
HSW4HMetazoa (kingdom)Ank_2,Ank_4,Ank
942WBChordata (phylum)Ank_2,Ank_4,Ank
5RC3TSarcopterygii (superclass)Ank_2,Ank,Ank_4
8ZB7HMammalia (class)Ank_2,Ank,Ank_4
4RHVBEuarchontoglires (superorder)Ank_2,Ank,Ank_4
4ZR8GPrimates (order)Ank,Ank_2,Ank_4
98MB3Haplorrhini (suborder)Ank_2,Ank,Ank_4
BV50MSimiiformes (infraorder)Ank,Ank_2,Ank_4
9EQ7RCatarrhini (parvorder)Ank,Ank_2,Ank_4
7J8U1Opisthokonta (clade)Ank_2,Ank_4,Ank
9G5TWVertebrata (clade)Ank_2,Ank_4,Ank
H560CBilateria (clade)Ank_2,Ank_4,Ank
FX07THominoidea (superfamily)Ank_2,Ank_4,Ank
5N406Hominidae (family)Ank,Ank_2,Ank_4
5XTC0Homininae (subfamily)Ank,Ank_2,Ank_4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: