Domains within Homo sapiens protein IL20_HUMAN (Q9NYY1)

Interleukin-20

Alternative representations: 1 /

Protein length176 aa
Source databaseUniProt
Identifiers IL20_HUMAN, Q9NYY1, ENSP00000356065.1, ENSP00000356065, ENSP00000356063.3, ENSP00000356063, Q17RB3, Q2THG6, Q96QZ6, H2Q107_PANTR, H2Q107
Source gene ENSG00000162891
Alternative splicing IL20_HUMAN, ENSP00000375796.2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

IL20_HUMAN is shown as IL20 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for IL20

Protein IL20_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04630JAK-STAT signaling pathway

KEGG orthologous groups

KONameDescription
K22667IL20interleukin 20

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000356065 in eggNOG.

OGTaxonomic classDescription
77U2MAll organisms (root)interleukin 19,interleukin 20
5EZSQEukaryota (superkingdom)interleukin 19,interleukin 20
HUR3HMetazoa (kingdom)interleukin 19,interleukin 20
93FNRChordata (phylum)interleukin 19,interleukin 20
5QBXTSarcopterygii (superclass)interleukin 19,interleukin 20
8YWF6Mammalia (class)interleukin 20
4RP36Euarchontoglires (superorder)interleukin 20
4ZX5XPrimates (order)interleukin 20
98Q0YHaplorrhini (suborder)interleukin 20
BVCXUSimiiformes (infraorder)interleukin 20
9ENMXCatarrhini (parvorder)interleukin 20
9G75UVertebrata (clade)interleukin 19,interleukin 20
H55PBBilateria (clade)interleukin 19,interleukin 20
7KUPNOpisthokonta (clade)interleukin 19,interleukin 20
FXBWTHominoidea (superfamily)interleukin 20
5MZ6UHominidae (family)interleukin 20
5Y1MKHomininae (subfamily)interleukin 20

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: