Domains within Homo sapiens protein IFNK_HUMAN (Q9P0W0)

Interferon kappa

Alternative representations: 1 /

Protein length207 aa
Source databaseUniProt
Identifiers IFNK_HUMAN, Q9P0W0, ENSP00000276943.2, ENSP00000276943, Q5T166
Source gene ENSG00000147896

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

IFNK_HUMAN is shown as IFNK in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for IFNK

Protein IFNK_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04630JAK-STAT signaling pathway

KEGG orthologous groups

KONameDescription
K05441IFNKinterferon kappa
K05414IFNAinterferon alpha

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000276943 in eggNOG.

OGTaxonomic classDescription
71YJRAll organisms (root)interferon alpha,interferon omega,interferon beta
5IH8GEukaryota (superkingdom)interferon alpha,interferon omega,interferon beta
HUF14Metazoa (kingdom)interferon alpha,interferon omega,interferon kappa
94V0UChordata (phylum)interferon alpha,interferon kappa,interferon epsilon
5QR9DSarcopterygii (superclass)interferon alpha,interferon kappa,interferon epsilon
8Z99GMammalia (class)interferon kappa
4R89MEuarchontoglires (superorder)interferon kappa
4ZNQFPrimates (order)interferon kappa
98DWWHaplorrhini (suborder)interferon kappa
BVFD6Simiiformes (infraorder)interferon kappa
9EGNPCatarrhini (parvorder)interferon kappa
H63FNBilateria (clade)interferon alpha,interferon omega,interferon kappa
7IZH3Opisthokonta (clade)interferon alpha,interferon omega,interferon kappa
9G8WYVertebrata (clade)interferon alpha,interferon kappa,interferon epsilon
FX2UFHominoidea (superfamily)interferon kappa
5NE3ZHominidae (family)interferon kappa
5Y0WRHomininae (subfamily)interferon kappa

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: