Domains within Rattus norvegicus protein PACN2_RAT (Q9QY17)

Protein kinase C and casein kinase substrate in neurons 2 protein

Alternative representations: 1 /

Protein length488 aa
Source databaseUniProt
Identifiers PACN2_RAT, Q9QY17, ENSRNOP00000060074.3, ENSRNOP00000060074, Q9QY18, Q9QY19, Q9QY20
Source gene ENSRNOG00000009756
Alternative splicing Q6IRI3_RAT, R9PXU3_RAT, PACN2_RAT

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

PACN2_RAT is shown as Pacsin2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Pacsin2

Protein PACN2_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05130Pathogenic Escherichia coli infection

KEGG orthologous groups

KONameDescription
K20123PACSINprotein kinase C and casein kinase substrate in neurons protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000060074 in eggNOG.

OGTaxonomic classDescription
LKOG2856All organisms (root)protein kinase C and casein kinase substrate in neurons protein,SH3 domain-containing protein 21,BAI1-associated protein 2
KOG2856Eukaryota (superkingdom)protein kinase C and casein kinase substrate in neurons protein,SH3 domain-containing protein 21,BAI1-associated protein 2
HTCYRMetazoa (kingdom)protein kinase C and casein kinase substrate in neurons protein,apolipoprotein L
944GFChordata (phylum)protein kinase C and casein kinase substrate in neurons protein
5QZ6SSarcopterygii (superclass)protein kinase C and casein kinase substrate in neurons protein
8ZGWYMammalia (class)protein kinase C and casein kinase substrate in neurons protein
4R5MIEuarchontoglires (superorder)protein kinase C and casein kinase substrate in neurons protein
AHXRDRodentia (order)protein kinase C and casein kinase substrate in neurons protein
8D3JUMyomorpha (suborder)protein kinase C and casein kinase substrate in neurons protein
9GU5QVertebrata (clade)protein kinase C and casein kinase substrate in neurons protein
7HH8COpisthokonta (clade)protein kinase C and casein kinase substrate in neurons protein,apolipoprotein L
H66ZJBilateria (clade)protein kinase C and casein kinase substrate in neurons protein
CQEZRMuridae (family)protein kinase C and casein kinase substrate in neurons protein
AE8MYMurinae (subfamily)protein kinase C and casein kinase substrate in neurons protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: