Domains within Homo sapiens protein FBX10_HUMAN (Q9UK96)

F-box only protein 10

Alternative representations: 1 /

Protein length956 aa
Source databaseUniProt
Identifiers FBX10_HUMAN, Q9UK96, ENSP00000403802.2, ENSP00000403802, Q08AL3, Q08AL4, Q5JRT8, Q9UKC3
Source gene ENSG00000147912
Alternative splicing FBX10_HUMAN, J3KN78_HUMAN, ENSP00000440061.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

FBX10_HUMAN is shown as FBXO10 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for FBXO10

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 7 PTMs annotated in this protein:

PTMCount
Phosphorylation7

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein FBXO10.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000403802 in eggNOG.

OGTaxonomic classDescription
LKOG1777All organisms (root)F-box protein 11,F-box protein 15,F-box protein 36
KOG1777Eukaryota (superkingdom)F-box protein 11,F-box protein 15,F-box protein 36
HTD89Metazoa (kingdom)F-box protein 10,F-box protein 11
93PMTChordata (phylum)F-box protein 10
5R7HMSarcopterygii (superclass)F-box protein 10
8ZN92Mammalia (class)F-box protein 10
4R50CEuarchontoglires (superorder)F-box protein 10
502C3Primates (order)F-box protein 10
98KJJHaplorrhini (suborder)F-box protein 10
BVDCBSimiiformes (infraorder)F-box protein 10
9EF5YCatarrhini (parvorder)F-box protein 10
9GAHBVertebrata (clade)F-box protein 10
H5MX3Bilateria (clade)F-box protein 10
7IW8WOpisthokonta (clade)F-box protein 10,F-box protein 11
FXEZ1Hominoidea (superfamily)F-box protein 10
5MXDDHominidae (family)F-box protein 10
5XUJIHomininae (subfamily)F-box protein 10

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: