Domains within Homo sapiens protein IQEC3_HUMAN (Q9UPP2)

IQ motif and SEC7 domain-containing protein 3

Alternative representations: 1 /

Protein length1182 aa
Source databaseUniProt
Identifiers IQEC3_HUMAN, Q9UPP2, ENSP00000437554.1, ENSP00000437554, A6NIF2, A6NKV9, Q8TB43, A0A0G2JLG2_HUMAN, A0A0G2JLG2, A0A0G2JN53_HUMAN, A0A0G2JN53
Source gene ENSG00000120645
Alternative splicing IQEC3_HUMAN, Q9UPP2-2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Fungi/Metazoa group

Predicted functional partners

IQEC3_HUMAN is shown as IQSEC3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for IQSEC3

Protein IQEC3_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04144Endocytosis

KEGG orthologous groups

KONameDescription
K12495IQSECIQ motif and SEC7 domain-containing protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000437554 in eggNOG.

OGTaxonomic classDescription
LKOG0931All organisms (root)IQ motif and SEC7 domain-containing protein
KOG0931Eukaryota (superkingdom)IQ motif and SEC7 domain-containing protein
HUSJXMetazoa (kingdom)IQ motif and SEC7 domain-containing protein
94VRMChordata (phylum)IQ motif and SEC7 domain-containing protein
5QZ9CSarcopterygii (superclass)IQ motif and SEC7 domain-containing protein
8Z42AMammalia (class)IQ motif and SEC7 domain-containing protein
4RAJIEuarchontoglires (superorder)IQ motif and SEC7 domain-containing protein
503JWPrimates (order)IQ motif and SEC7 domain-containing protein
988T2Haplorrhini (suborder)IQ motif and SEC7 domain-containing protein
BV6BWSimiiformes (infraorder)IQ motif and SEC7 domain-containing protein
9EX82Catarrhini (parvorder)IQ motif and SEC7 domain-containing protein
7M5PVOpisthokonta (clade)IQ motif and SEC7 domain-containing protein
9FGBKVertebrata (clade)IQ motif and SEC7 domain-containing protein
H58E2Bilateria (clade)IQ motif and SEC7 domain-containing protein
FX2SSHominoidea (superfamily)IQ motif and SEC7 domain-containing protein
5N2Y9Hominidae (family)IQ motif and SEC7 domain-containing protein
5Y3B1Homininae (subfamily)IQ motif and SEC7 domain-containing protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: