Domains within Homo sapiens protein SMAG1_HUMAN (Q9UPU9)

Protein Smaug homolog 1

Alternative representations: 1 /

Protein length718 aa
Source databaseUniProt
Identifiers SMAG1_HUMAN, Q9UPU9, ENSP00000452535.1, ENSP00000452535, ENSP00000375919.3, ENSP00000375919, A8MPZ5, Q0VA96, Q6PEW4, Q9UPU9-2
Source gene ENSG00000020577
Alternative splicing SMAG1_HUMAN, Q9UPU9-3, G3V2R1_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

SMAG1_HUMAN is shown as SAMD4A in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SAMD4A

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000452535 in eggNOG.

OGTaxonomic classDescription
LKOG3791All organisms (root)SAM_2,SAM_1,zf-CCHC
KOG3791Eukaryota (superkingdom)SAM_2,SAM_1,zf-CCHC
HVMI7Metazoa (kingdom)SAM_1,PHAT,SAM_2
94RP7Chordata (phylum)SAM_1,PHAT
5QNIWSarcopterygii (superclass)SAM_1,PHAT
8YUGYMammalia (class)SAM_1,PHAT
4RAKKEuarchontoglires (superorder)SAM_1,PHAT
4ZR06Primates (order)SAM_1
98PXIHaplorrhini (suborder)SAM_1
BVJC5Simiiformes (infraorder)SAM_1
9EISDCatarrhini (parvorder)SAM_1
9FCCSVertebrata (clade)SAM_1,PHAT
H6BCNBilateria (clade)SAM_1,PHAT,SAM_2
7H9B8Opisthokonta (clade)SAM_2,SAM_1,PHAT
FXCXKHominoidea (superfamily)SAM_1
5NDEAHominidae (family)SAM_1
5Y3GWHomininae (subfamily)SAM_1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: