Domains within Pyrococcus abyssi GE5 protein RFCS_PYRAB (Q9V2G4)
Replication factor C small subunit
Alternative representations: 1 /
| Protein length | 1437 aa |
|---|---|
| Source database | UniProt |
| Identifiers | G8ZFU5, RFCS_PYRAB, Q9V2G4 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
RFCS_PYRAB is shown as 
rfcS in the network
Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.
The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein RFCS_PYRAB is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map03030 | DNA replication |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K02341 | holB | DNA polymerase III subunit delta' [EC:2.7.7.7] | iPath3 |
| K04801 | rfcS | replication factor C small subunit | |
| K14415 | RTCB, rtcB | tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 272844.PAB0068 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG0470 | All organisms (root) | DNA polymerase III subunit delta' [EC:2.7.7.7],replication factor C subunit 3/5,replication factor C subunit 2/4 |
| 737HY | All organisms (root) | replication factor C small subunit,V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1],ATP-dependent helicase Lhr and Lhr-like helicase [EC:3.6.4.13 5.6.2.4] |
| 72MCV | All organisms (root) | tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8],ATP-dependent Lon protease [EC:3.4.21.53],replicative DNA helicase Mcm [EC:5.6.2.3] |
| arCOG03158 | Archaea (superkingdom) | tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8],ATP-dependent Lon protease [EC:3.4.21.53],replicative DNA helicase Mcm [EC:5.6.2.3] |
| arCOG03154 | Archaea (superkingdom) | replication factor C small subunit,V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1],ATP-dependent helicase Lhr and Lhr-like helicase [EC:3.6.4.13 5.6.2.4] |
| arCOG00469 | Archaea (superkingdom) | replication factor C small subunit,putative ATPase,holliday junction DNA helicase RuvB [EC:5.6.2.4] |
| EKIFV | Euryarchaeota (phylum) | replication factor C small subunit |
| EFRNX | Thermococcaceae (family) | replication factor C small subunit |
| AJ56M | Pyrococcus (genus) | replication factor C small subunit |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.