Domains within Drosophila melanogaster protein ADAT1_DROME (Q9V3R6)

tRNA-specific adenosine deaminase 1

Alternative representations: 1 /

Protein length394 aa
Source databaseUniProt
Identifiers ADAT1_DROME, Q9V3R6, FBPP0304017, FBPP0080150, M9PDF5_DROME, M9PDF5, N0BSY1_DROME, N0BSY1
Source gene FBgn0028658

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

ADAT1_DROME is shown as Adat1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Adat1

Protein ADAT1_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05171Coronavirus disease - COVID-19

KEGG orthologous groups

KONameDescription
K15440TAD1, ADAT1tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 6 PTMs annotated in this protein:

PTMCount
Phosphorylation5
Methylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein adat.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0080150 in eggNOG.

OGTaxonomic classDescription
FV5Z5melanogaster group (species group)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
FE0QCmelanogaster subgroup (species subgroup)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
LKOG2777All organisms (root)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34],double stranded RNA-specific editase B [EC:3.5.-.-],double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
EIYPUEndopterygota (cohort)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
KOG2777Eukaryota (superkingdom)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34],double stranded RNA-specific editase B [EC:3.5.-.-],double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
HUSWTMetazoa (kingdom)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
HIPAFArthropoda (phylum)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
85W0JHexapoda (subphylum)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
AHH1XNeoptera (infraclass)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
ANC1VDiptera (order)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
H5NP0Bilateria (clade)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
7JZ6XOpisthokonta (clade)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34],double stranded RNA-specific editase B [EC:3.5.-.-]
EGUB9Drosophila (genus)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
50HYRSophophora (subgenus)tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: