Domains within Drosophila melanogaster protein A0A0B4KGU2_DROME (A0A0B4KGU2)

Lute, isoform D

Alternative representations: 1 /

Protein length735 aa
Source databaseUniProt
Identifiers A0A0B4KGU2_DROME, A0A0B4KGU2, FBPP0303070, Q9VEL0_DROME, Q9VEL0
Source gene FBgn0262871
Alternative splicing A0A0B4KGU2_DROME, FBpp0082876, C7LAF3_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

A0A0B4KGU2_DROME is shown as lute in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for lute

Protein A0A0B4KGU2_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04340Hedgehog signaling pathway

KEGG orthologous groups

KONameDescription
K10477BTBD1_2BTB/POZ domain-containing protein 1/2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0303070 in eggNOG.

OGTaxonomic classDescription
FUYWXmelanogaster group (species group)BTB/POZ domain-containing protein 3/6
FE3SFmelanogaster subgroup (species subgroup)BTB/POZ domain-containing protein 3/6
EIE6QEndopterygota (cohort)BTB/POZ domain-containing protein 3/6
LKOG2075All organisms (root)BTB/POZ domain-containing protein 1/2,BTB/POZ domain-containing protein 3/6,BTB/POZ domain-containing protein 17
KOG2075Eukaryota (superkingdom)BTB/POZ domain-containing protein 1/2,BTB/POZ domain-containing protein 3/6,BTB/POZ domain-containing protein 17
HW5TTMetazoa (kingdom)BTB/POZ domain-containing protein 3/6,BTB/POZ domain-containing protein 1/2
HISWGArthropoda (phylum)BTB/POZ domain-containing protein 3/6,BTB/POZ domain-containing protein 1/2
86IDGHexapoda (subphylum)BTB/POZ domain-containing protein 3/6,BTB/POZ domain-containing protein 1/2
AHC7FNeoptera (infraclass)BTB/POZ domain-containing protein 3/6,BTB/POZ domain-containing protein 1/2
ANC3IDiptera (order)BTB/POZ domain-containing protein 3/6
7M0H6Opisthokonta (clade)BTB/POZ domain-containing protein 3/6,BTB/POZ domain-containing protein 1/2
H6ZF4Bilateria (clade)BTB/POZ domain-containing protein 3/6,BTB/POZ domain-containing protein 1/2
EGTJXDrosophila (genus)BTB/POZ domain-containing protein 3/6
50MRYSophophora (subgenus)BTB/POZ domain-containing protein 3/6

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: