Domains within Drosophila melanogaster protein Q9VQK5_DROME (Q9VQK5)

CG3542

Alternative representations: 1 /

Protein length806 aa
Source databaseUniProt
Identifiers Q9VQK5_DROME, Q9VQK5, FBPP0077333, Q9VQK6
Source gene FBgn0031492

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

Q9VQK5_DROME is shown as Prp40 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Prp40

Protein Q9VQK5_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03040Spliceosome

KEGG orthologous groups

KONameDescription
K12821PRPF40, PRP40pre-mRNA-processing factor 40

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 22 PTMs annotated in this protein:

PTMCount
Phosphorylation17
Acetylation5

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein CG3542.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0077333 in eggNOG.

OGTaxonomic classDescription
LKOG0152All organisms (root)pre-mRNA-processing factor 40,WW domain-containing adapter protein with coiled-coil,polyglutamine-binding protein 1
FDYMMmelanogaster subgroup (species subgroup)pre-mRNA-processing factor 40
EIPRJEndopterygota (cohort)pre-mRNA-processing factor 40
FUYQ5melanogaster group (species group)pre-mRNA-processing factor 40
KOG0152Eukaryota (superkingdom)pre-mRNA-processing factor 40,WW domain-containing adapter protein with coiled-coil,polyglutamine-binding protein 1
HSRYAMetazoa (kingdom)pre-mRNA-processing factor 40
HI5K9Arthropoda (phylum)pre-mRNA-processing factor 40
85HW6Hexapoda (subphylum)pre-mRNA-processing factor 40
AH49PNeoptera (infraclass)pre-mRNA-processing factor 40
ANC62Diptera (order)pre-mRNA-processing factor 40
H3EXTBilateria (clade)pre-mRNA-processing factor 40
7I9QBOpisthokonta (clade)pre-mRNA-processing factor 40
EH03JDrosophila (genus)pre-mRNA-processing factor 40
50M3XSophophora (subgenus)pre-mRNA-processing factor 40

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: