Domains within Drosophila melanogaster protein INSL3_DROME (Q9VT52)

Probable insulin-like peptide 3

Alternative representations: 1 /

Protein length120 aa
Source databaseUniProt
Identifiers INSL3_DROME, Q9VT52, FBPP0076102, Q4V6B2_DROME, Q4V6B2, E7BBS2_DROME, E7BBS2
Source gene FBgn0044050

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

INSL3_DROME is shown as Ilp3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ilp3

Protein INSL3_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04211Longevity regulating pathway

KEGG orthologous groups

KONameDescription
K04526INSinsulin

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0076102 in eggNOG.

OGTaxonomic classDescription
714TCAll organisms (root)insulin
FE2YImelanogaster subgroup (species subgroup)insulin
FV4Z7melanogaster group (species group)insulin
EJ1RWEndopterygota (cohort)insulin
5FNT7Eukaryota (superkingdom)insulin
HV42CMetazoa (kingdom)insulin
HIU2EArthropoda (phylum)insulin
85EWUHexapoda (subphylum)insulin
AH3SKNeoptera (infraclass)insulin
ANVMCDiptera (order)insulin
H5YUGBilateria (clade)insulin
7KBX1Opisthokonta (clade)insulin
EH1KTDrosophila (genus)insulin
50FI8Sophophora (subgenus)insulin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: