Domains within Drosophila melanogaster protein Q9VXE8_DROME (Q9VXE8)

RE34144p

Alternative representations: 1 /

Protein length167 aa
Source databaseUniProt
Identifiers Q9VXE8_DROME, Q9VXE8, FBPP0074058, FBPP0309143
Source gene FBgn0267384

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

Q9VXE8_DROME is shown as Ubc7 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ubc7

Protein Q9VXE8_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04120Ubiquitin mediated proteolysis
map04141Protein processing in endoplasmic reticulum

KEGG orthologous groups

KONameDescription
K04555UBE2G2, UBC7ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Ubiquitination2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein crl.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0309143 in eggNOG.

OGTaxonomic classDescription
LKOG0426All organisms (root)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23],dentin sialophosphoprotein,ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
EIE3KEndopterygota (cohort)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
FV1S5melanogaster group (species group)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
FE0Q8melanogaster subgroup (species subgroup)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
KOG0426Eukaryota (superkingdom)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23],dentin sialophosphoprotein,ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
HU37UMetazoa (kingdom)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23],small ubiquitin-related modifier
HI3GQArthropoda (phylum)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
8651DHexapoda (subphylum)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
AGXTDNeoptera (infraclass)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
ANH7PDiptera (order)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
7MXYMOpisthokonta (clade)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23],dentin sialophosphoprotein,small ubiquitin-related modifier
H3H6UBilateria (clade)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23],small ubiquitin-related modifier
EH209Drosophila (genus)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
50CHXSophophora (subgenus)ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: