Domains within Drosophila melanogaster protein BAP60_DROME (Q9VYG2)

Brahma-associated protein of 60 kDa

Alternative representations: 1 /

Protein length515 aa
Source databaseUniProt
Identifiers BAP60_DROME, Q9VYG2, FBPP0073572, O76490, B4R428_DROSI, B4R428
Source gene FBgn0025463

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

BAP60_DROME is shown as Bap60 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Bap60

Protein BAP60_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05225Hepatocellular carcinoma

KEGG orthologous groups

KONameDescription
K11650SMARCDSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 17 PTMs annotated in this protein:

PTMCount
Phosphorylation11
Ubiquitination5
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Bap60.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0073572 in eggNOG.

OGTaxonomic classDescription
FV0QSmelanogaster group (species group)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
FE4RGmelanogaster subgroup (species subgroup)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
LCOG5531All organisms (root)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D,upstream activation factor subunit UAF30,SWI/SNF complex component SWP73
EIK9HEndopterygota (cohort)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
KOG2570Eukaryota (superkingdom)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D,SWI/SNF complex component SWP73,chromatin structure-remodeling complex subunit RSC6
HU48WMetazoa (kingdom)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D,methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
HISIIArthropoda (phylum)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
8615NHexapoda (subphylum)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
AH4WSNeoptera (infraclass)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
ANZFVDiptera (order)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
7I4CTOpisthokonta (clade)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D,SWI/SNF complex component SWP73,chromatin structure-remodeling complex subunit RSC6
H5X22Bilateria (clade)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D,methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
EH03NDrosophila (genus)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
50M4SSophophora (subgenus)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: