Domains within Drosophila melanogaster protein PGPSA_DROME (Q9VYX7)

Peptidoglycan-recognition protein SA

Alternative representations: 1 /

Protein length203 aa
Source databaseUniProt
Identifiers PGPSA_DROME, Q9VYX7, FBPP0073358, FBPP0309257, F6J5T4_DROME, F6J5T4, X2JEI8_DROME, X2JEI8
Source gene FBgn0030310

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

PGPSA_DROME is shown as PGRP-SA in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for PGRP-SA

Protein PGPSA_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04624Toll and Imd signaling pathway
map00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis iPath3
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

KONameDescription
K05293PIGUGPI-anchor transamidase subunit U iPath3
K01446PGRPpeptidoglycan recognition protein
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0073358 in eggNOG.

OGTaxonomic classDescription
FUZIHmelanogaster group (species group)peptidoglycan recognition protein
FDY40melanogaster subgroup (species subgroup)peptidoglycan recognition protein
LKOG2552All organisms (root)GPI-anchor transamidase subunit U,peptidoglycan recognition protein,peptidoglycan recognition protein LC
EJB55Endopterygota (cohort)peptidoglycan recognition protein
KOG2552Eukaryota (superkingdom)GPI-anchor transamidase subunit U,peptidoglycan recognition protein,peptidoglycan recognition protein LC
HUQT8Metazoa (kingdom)peptidoglycan recognition protein
HHTE4Arthropoda (phylum)peptidoglycan recognition protein
85CNFHexapoda (subphylum)peptidoglycan recognition protein
AH59ANeoptera (infraclass)peptidoglycan recognition protein
ANIA9Diptera (order)peptidoglycan recognition protein
H3UTFBilateria (clade)peptidoglycan recognition protein
7KXMXOpisthokonta (clade)peptidoglycan recognition protein
EGYHQDrosophila (genus)peptidoglycan recognition protein
50CT2Sophophora (subgenus)peptidoglycan recognition protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: