Domains within Homo sapiens protein SO1B1_HUMAN (Q9Y6L6)

Solute carrier organic anion transporter family member 1B1

Alternative representations: 1 /

Protein length691 aa
Source databaseUniProt
Identifiers SO1B1_HUMAN, Q9Y6L6, ENSP00000256958.2, ENSP00000256958, B2R7G2, Q29R64, Q9NQ37, Q9UBF3, Q9UH89, A0A024RAU7_HUMAN, A0A024RAU7, K4P403_HUMAN, K4P403
Source gene ENSG00000134538

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

SO1B1_HUMAN is shown as SLCO1B1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SLCO1B1

Protein SO1B1_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04919Thyroid hormone signaling pathway
map04976Bile secretion

KEGG orthologous groups

KONameDescription
K14354SLCO4Asolute carrier organic anion transporter family, member 4A
K14353SLCO3Asolute carrier organic anion transporter family, member 3A
K05043SLCO1Bsolute carrier organic anion transporter family, member 1B
K08747SLCO1Csolute carrier organic anion transporter family, member 1C

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 18 PTMs annotated in this protein:

PTMCount
Phosphorylation16
Acetylation1
N-linked glycosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein SLCO1B1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000256958 in eggNOG.

OGTaxonomic classDescription
LKOG3626All organisms (root)solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C
KOG3626Eukaryota (superkingdom)solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C
HUBUPMetazoa (kingdom)solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C
93WD2Chordata (phylum)solute carrier organic anion transporter family, member 1C,solute carrier organic anion transporter family, member 1A,solute carrier organic anion transporter family, member 1B
5R3XQSarcopterygii (superclass)solute carrier organic anion transporter family, member 1C,solute carrier organic anion transporter family, member 1B,solute carrier organic anion transporter family, member 1A
8ZMI0Mammalia (class)solute carrier organic anion transporter family, member 1B
4RS2TEuarchontoglires (superorder)solute carrier organic anion transporter family, member 1B
4ZSKYPrimates (order)solute carrier organic anion transporter family, member 1B
98F2FHaplorrhini (suborder)solute carrier organic anion transporter family, member 1B
BVIAUSimiiformes (infraorder)solute carrier organic anion transporter family, member 1B
9EQMXCatarrhini (parvorder)solute carrier organic anion transporter family, member 1B
H6B1CBilateria (clade)solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C,solute carrier organic anion transporter family, member 4A
7N0JWOpisthokonta (clade)solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C
9G1U5Vertebrata (clade)solute carrier organic anion transporter family, member 1C,solute carrier organic anion transporter family, member 1B,solute carrier organic anion transporter family, member 1A
FX29YHominoidea (superfamily)solute carrier organic anion transporter family, member 1B
5N2EKHominidae (family)solute carrier organic anion transporter family, member 1B
5Y5S1Homininae (subfamily)solute carrier organic anion transporter family, member 1B

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: