Domains within Mus musculus protein GIPC1_MOUSE (Q9Z0G0)

PDZ domain-containing protein GIPC1

Alternative representations: 1 /

Protein length333 aa
Source databaseUniProt
Identifiers GIPC1_MOUSE, Q9Z0G0, ENSMUSP00000019577.8, ENSMUSP00000019577, A0A1D5RML2_MOUSE, A0A1D5RML2
Source gene ENSMUSG00000019433
Alternative splicing GIPC1_MOUSE, ENSMUSP00000148847.1, ENSMUSP00000148824.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

GIPC1_MOUSE is shown as Gipc1 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Gipc1

Protein GIPC1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04141Protein processing in endoplasmic reticulum
map04114Oocyte meiosis

KEGG orthologous groups

KONameDescription
K20056GIPC, SEMCAPPDZ domain-containing protein GIPC

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 20 PTMs annotated in this protein:

PTMCount
Phosphorylation8
Ubiquitination5
Acetylation4
Methylation3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Gipc1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000019577 in eggNOG.

OGTaxonomic classDescription
LKOG3938All organisms (root)speedy,PDZ domain-containing protein GIPC,DnaJ homolog subfamily B member 1
KOG3938Eukaryota (superkingdom)PDZ domain-containing protein GIPC,DnaJ homolog subfamily B member 1
HU6T7Metazoa (kingdom)PDZ domain-containing protein GIPC,DnaJ homolog subfamily B member 1
93QU1Chordata (phylum)PDZ domain-containing protein GIPC,DnaJ homolog subfamily B member 1
5QB44Sarcopterygii (superclass)PDZ domain-containing protein GIPC,DnaJ homolog subfamily B member 1
8ZGH3Mammalia (class)PDZ domain-containing protein GIPC
4R6FPEuarchontoglires (superorder)PDZ domain-containing protein GIPC
AIDITRodentia (order)PDZ domain-containing protein GIPC
8DC5GMyomorpha (suborder)PDZ domain-containing protein GIPC
9FZ7HVertebrata (clade)PDZ domain-containing protein GIPC,DnaJ homolog subfamily B member 1
7KTFROpisthokonta (clade)PDZ domain-containing protein GIPC,DnaJ homolog subfamily B member 1
H73GWBilateria (clade)PDZ domain-containing protein GIPC,DnaJ homolog subfamily B member 1
CQFUKMuridae (family)PDZ domain-containing protein GIPC
ADYV3Murinae (subfamily)PDZ domain-containing protein GIPC
5PYB3Mus (genus)PDZ domain-containing protein GIPC
HE9DWMus (subgenus)PDZ domain-containing protein GIPC

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: