SMART can predict possible catalytic inactivity, based on the presence of essential amino acids at specific positions in the alignment. If any of the required amino acids are missing, the domain is marked as 'inactive'. Check the annotation page for details. Only returned for features with type 'SMART'. HTTP link to the SMART domain annotation page. Only returned for features with type 'SMART'. HTTP link which can be used to generate the SMART protein schematic in PNG format. User can submit either a protein sequence or Uniprot/Ensembl identifier. If both a sequence and an ID are supplied, ID will be used. Only sequences that are present in the SMART database will be accepted (Uniprot100 and Ensembl proteomes).

SMART webservice