The domain within your query sequence starts at position 1669 and ends at position 1897; the E-value for the AAA domain shown below is 9e-84.

VRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEFKIINPKAITMGQLYGCFD
AVSHEWTDGVLANAFREQASSITDDRKWIIFDGPVDAVWIENMNTVLDDNKKLCLMSGEI
IQMSSKMSLIFEPADLEQASPATVSRCGMIYMEAHQLGWKPLKDSYMDTLPRCLTKEHTE
LVEDMFTWLVQPCLDFSRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRD

The domain was found using the schnipsel database

AAA

ATPases associated with a variety of cellular activities

• SMART accession number: SM00382
• Description: AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
• Interpro abstract (IPR003593):

  The AAA+ superfamily of ATPases is found in all kingdoms of living organisms where they participate in diverse cellular processes including membrane fusion, proteolysis and DNA replication. Although the terms AAA+ and AAA are often used loosely and interchangeably, the classical AAA family members are distinguished by their possession of the SRH region in the AAA module. Many AAA+ proteins are involved in similar processes to those of AAA proteins (facilitation of protein folding and unfolding, assembly or disassembly of proteins complexes, protein transport and degradation), but others function in replication, recombination, repair and transcription. For a review see [ (PUBMED:11473577) ].

  The proteins in this superfamily are characterised by the structural conservation of a central ATPase domain of about 250 amino acids called the AAA+ module. Typically, the AAA+ domain can be divided into two structural subdomains, an N-terminal P-loop NTPase alpha-beta-alpha subdomain that is connected to a smaller C-terminal all-alpha subdomain. The alpha-beta-alpha subdomain adopts a Rossman fold and contains several motifs involved in ATP binding and hydrolysis, including classical motifs Walker A and Walker B [ (PUBMED:11473577) (PUBMED:18466635) ]. The all-alpha subdomain [ (PUBMED:9927482) ], is much less conserved across AAA+ proteins.

There are 2804801 AAA domains in 2428284 proteins in SMART's nrdb database.

Literature (relevant references for this domain)

Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.

• Neuwald AF, Aravind L, Spouge JL, Koonin EV
• AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes.
• Genome Res. 1999; 9: 27-43

Using a combination of computer methods for iterative database searches and multiple sequence alignment, we show that protein sequences related to the AAA family of ATPases are far more prevalent than reported previously. Among these are regulatory components of Lon and Clp proteases, proteins involved in DNA replication, recombination, and restriction (including subunits of the origin recognition complex, replication factor C proteins, MCM DNA-licensing factors and the bacterial DnaA, RuvB, and McrB proteins), prokaryotic NtrC-related transcription regulators, the Bacillus sporulation protein SpoVJ, Mg2+, and Co2+ chelatases, the Halobacterium GvpN gas vesicle synthesis protein, dynein motor proteins, TorsinA, and Rubisco activase. Alignment of these sequences, in light of the structures of the clamp loader delta' subunit of Escherichia coli DNA polymerase III and the hexamerization component of N-ethylmaleimide-sensitive fusion protein, provides structural and mechanistic insights into these proteins, collectively designated the AAA+ class. Whole-genome analysis indicates that this class is ancient and has undergone considerable functional divergence prior to the emergence of the major divisions of life. These proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. The hexameric architecture often associated with this class can provide a hole through which DNA or RNA can be thread; this may be important for assembly or remodeling of DNA-protein complexes.

• Lenzen CU, Steinmann D, Whiteheart SW, Weis WI
• Crystal structure of the hexamerization domain of N-ethylmaleimide-sensitive fusion protein.
• Cell. 1998; 94: 525-36

N-ethylmaleimide-sensitive fusion protein (NSF) is a cytosolic ATPase required for many intracellular vesicle fusion reactions. NSF consists of an amino-terminal region that interacts with other components of the vesicle trafficking machinery, followed by two homologous ATP-binding cassettes, designated D1 and D2, that possess essential ATPase and hexamerization activities, respectively. The crystal structure of D2 bound to Mg2+-AMPPNP has been determined at 1.75 A resolution. The structure consists of a nucleotide-binding and a helical domain, and it is unexpectedly similar to the first two domains of the clamp-loading subunit delta' of E. coli DNA polymerase III. The structure suggests several regions responsible for coupling of ATP hydrolysis to structural changes in full-length NSF.

• Patel S, Latterich M
• The AAA team: related ATPases with diverse functions.
• Trends Cell Biol. 1998; 8: 65-71

A new family of related ATPases has emerged, characterized by a highly conserved AAA motif. This motif forms a 230-amino-acid domain that contains Walker homology sequences and imparts ATPase activity. Homology between AAA-family members is confined mostly to the AAA domain, although additional homology outside the AAA motif is present among closely related proteins. AAA proteins act in a variety of cellular functions, including cell-cycle regulation, protein degradation, organelle biogenesis and vesicle-mediated protein transport. The AAA domain is required for protein function, but its exact role and the specific activity that it confers on AAA proteins is still unclear. This review describes current understanding of the AAA protein family.

Disease (disease genes where sequence variants are found in this domain)

SwissProt sequences and OMIM curated human diseases associated with missense mutations within the AAA domain.

Protein	Disease
Peroxisome biogenesis factor 1 (O43933) (SMART)	OMIM:602136: Zellweger syndrome-1 OMIM:214100: Adrenoleukodystrophy, neonatal OMIM:202370: Refsum disease, infantile OMIM:266510:
ATP-binding cassette sub-family D member 1 (P33897) (SMART)	OMIM:300100: Adrenoleukodystrophy ; Adrenomyeloneuropathy
Cystic fibrosis transmembrane conductance regulator (P13569) (SMART)	OMIM:602421: Cystic fibrosis OMIM:219700: Congenital bilateral absence of vas deferens OMIM:277180: Sweat chloride elevation without CF ; {Pancreatitis, idiopathic} ; {Hypertrypsinemia, neonatal}
ATP-binding cassette sub-family C member 8 (Q09428) (SMART)	OMIM:600509: Persistent hyperinsulinemic hypoglycemia of infancy OMIM:256450:
Spastin (Q9UBP0) (SMART)	OMIM:182601: Spastic paraplegia-4 OMIM:604277: Spastic paraplegia-4 OMIM:182601:
ATP-binding cassette sub-family A member 1 (O95477) (SMART)	OMIM:600046: Tangier disease OMIM:205400: HDL deficiency, familial OMIM:604091:
Antigen peptide transporter 1 (Q03518) (SMART)	OMIM:170260: TRANSPORTER, ATP-BINDING CASSETTE, MAJOR HISTOCOMPATIBILITY COMPLEX
DNA repair protein RAD51 homolog 1 (Q06609) (SMART)	OMIM:179617: {Breast cancer, susceptibility to} OMIM:114480:
Canalicular multispecific organic anion transporter 1 (Q92887) (SMART)	OMIM:601107: Dubin-Johnson syndrome OMIM:237500:
Antigen peptide transporter 2 (Q03519) (SMART)	OMIM:170261: Bare lymphocyte syndrome, type I, due to TAP2 deficiency
Peroxisome assembly factor 2 (Q13608) (SMART)	OMIM:601498: Peroxisomal biogenesis disorder, complementation group 4
Retinal-specific ATP-binding cassette transporter (P78363) (SMART)	OMIM:601691: Stargardt disease-1 OMIM:248200: Retinitis pigmentosa-19 OMIM:601718: Cone-rod dystrophy 3 ; Macular dystrophy, age-related, 2 OMIM:153800: Fundus flavimaculatus OMIM:248200:

Metabolism (metabolic pathways involving proteins which contain this domain)

% proteins involved	KEGG pathway ID	Description
72.32	map02010	ABC transporters - General
4.51	map03060	Protein export
3.93	map03030	DNA replication
3.06	map03090	Type II secretion system
2.69	map00190	Oxidative phosphorylation
1.92	map00195	Photosynthesis
1.85	map02020	Two-component system - General
1.57	map02040	Flagellar assembly
1.26	map03070	Type III secretion system
1.06	map00910	Nitrogen metabolism
0.87	map03050	Proteasome
0.79	map00790	Folate biosynthesis
0.75	map00860	Porphyrin and chlorophyll metabolism
0.67	map00500	Starch and sucrose metabolism
0.57	map04111	Cell cycle - yeast
0.56	map04110	Cell cycle
0.37	map00230	Purine metabolism
0.27	map03080	Type IV secretion system
0.15	map00240	Pyrimidine metabolism
0.14	map05212	Pancreatic cancer
0.11	map04310	Wnt signaling pathway
0.07	map04612	Antigen processing and presentation
0.06	map00400	Phenylalanine, tyrosine and tryptophan biosynthesis
0.06	map00920	Sulfur metabolism
0.06	map00450	Selenoamino acid metabolism
0.05	map00730	Thiamine metabolism
0.05	map04930	Type II diabetes mellitus
0.03	map00780	Biotin metabolism
0.03	map00310	Lysine degradation
0.02	map05120	Epithelial cell signaling in Helicobacter pylori infection
0.02	map00440	Aminophosphonate metabolism
0.02	map00540	Lipopolysaccharide biosynthesis
0.01	map00010	Glycolysis / Gluconeogenesis
0.01	map00271	Methionine metabolism
0.01	map00770	Pantothenate and CoA biosynthesis
0.01	map00260	Glycine, serine and threonine metabolism
0.01	map00350	Tyrosine metabolism
0.01	map00251	Glutamate metabolism
0.01	map00650	Butanoate metabolism
0.01	map00120	Bile acid biosynthesis
0.01	map00710	Carbon fixation
0.01	map00460	Cyanoamino acid metabolism
0.01	map00632	Benzoate degradation via CoA ligation
0.01	map00564	Glycerophospholipid metabolism
0.01	map00300	Lysine biosynthesis
0.01	map00903	Limonene and pinene degradation
0.01	map00624	1- and 2-Methylnaphthalene degradation
0.01	map00630	Glyoxylate and dicarboxylate metabolism
0.01	map00480	Glutathione metabolism
0.01	map00550	Peptidoglycan biosynthesis
0.01	map00362	Benzoate degradation via hydroxylation
0.01	map00272	Cysteine metabolism
0.01	map00030	Pentose phosphate pathway

This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with AAA domain which could be assigned to a KEGG orthologous group, and not all proteins containing AAA domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.

Structure (3D structures containing this domain)

3D Structures of AAA domains in PDB

PDB code	Title
1b0u	ATP-BINDING SUBUNIT OF THE HISTIDINE PERMEASE FROM SALMONELLA TYPHIMURIUM
1bmf	BOVINE MITOCHONDRIAL F1-ATPASE
1cow	BOVINE MITOCHONDRIAL F1-ATPASE COMPLEXED WITH AUROVERTIN B
1d2n	D2 DOMAIN OF N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN
1do0	ORTHORHOMBIC CRYSTAL FORM OF HEAT SHOCK LOCUS U (HSLU) FROM ESCHERICHIA COLI
1do2	TRIGONAL CRYSTAL FORM OF HEAT SHOCK LOCUS U (HSLU) FROM ESCHERICHIA COLI
1e1q	BOVINE MITOCHONDRIAL F1-ATPASE AT 100K
1e1r	BOVINE MITOCHONDRIAL F1-ATPASE INHIBITED BY MG2+ADP AND ALUMINIUM FLUORIDE
1e32	Structure of the N-Terminal domain and the D1 AAA domain of membrane fusion ATPase p97
1e69	SMC head domain from Thermotoga maritima
1e79	Bovine F1-ATPase inhibited by DCCD (dicyclohexylcarbodiimide)
1e94	HslV-HslU from E.coli
1efr	BOVINE MITOCHONDRIAL F1-ATPASE COMPLEXED WITH THE PEPTIDE ANTIBIOTIC EFRAPEPTIN
1f3o	Crystal structure of MJ0796 ATP-binding cassette
1f48	CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI ARSENITE-TRANSLOCATING ATPASE
1ffh	N AND GTPASE DOMAINS OF THE SIGNAL SEQUENCE RECOGNITION PROTEIN FFH FROM THERMUS AQUATICUS
1fnn	CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM
1fts	SIGNAL RECOGNITION PARTICLE RECEPTOR FROM E. COLI
1fx0	Crystal structure of the chloroplast F1-ATPase from spinach
1g18	RECA-ADP-ALF4 COMPLEX
1g19	STRUCTURE OF RECA PROTEIN
1g29	MALK
1g3i	CRYSTAL STRUCTURE OF THE HSLUV PROTEASE-CHAPERONE COMPLEX
1g41	CRYSTAL STRUCTURE OF HSLU HAEMOPHILUS INFLUENZAE
1g4a	CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM
1g4b	CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM
1g6h	CRYSTAL STRUCTURE OF THE ADP CONFORMATION OF MJ1267, AN ATP-BINDING CASSETTE OF AN ABC TRANSPORTER
1g8p	CRYSTAL STRUCTURE OF BCHI SUBUNIT OF MAGNESIUM CHELATASE
1g8y	CRYSTAL STRUCTURE OF THE HEXAMERIC REPLICATIVE HELICASE REPA OF PLASMID RSF1010
1g9x	CHARACTERIZATION OF THE TWINNING STRUCTURE OF MJ1267, AN ATP-BINDING CASSETTE OF AN ABC TRANSPORTER
1gaj	CRYSTAL STRUCTURE OF A NUCLEOTIDE-FREE ATP-BINDING CASSETTE FROM AN ABC TRANSPORTER
1h8e	(ADP.AlF4)2(ADP.SO4) bovine F1-ATPase (all three catalytic sites occupied)
1h8h	Bovine mitochondrial F1-Atpase at 100K
1hqc	STRUCTURE OF RUVB FROM THERMUS THERMOPHILUS HB8
1hqy	Nucleotide-Dependent Conformational Changes in a Protease-Associated ATPase HslU
1ht1	Nucleotide-Dependent Conformational Changes in a Protease-Associated ATPase HslU
1ht2	Nucleotide-Dependent Conformational Changes in a Protease-Associated ATPase HslU
1ihu	CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI ARSENITE-TRANSLOCATING ATPASE IN COMPLEX WITH MG-ADP-ALF3
1ii0	CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI ARSENITE-TRANSLOCATING ATPASE
1ii9	CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI ARSENITE-TRANSLOCATING ATPASE IN COMPLEX WITH AMP-PNP
1im2	HslU, Haemophilus Influenzae, Selenomethionine Variant
1in4	THERMOTOGA MARITIMA RUVB HOLLIDAY JUNCTION BRANCH MIGRATION MOTOR
1in5	THERMOGOTA MARITIMA RUVB A156S MUTANT
1in6	THERMOTOGA MARITIMA RUVB K64R MUTANT
1in7	THERMOTOGA MARITIMA RUVB R170A
1in8	THERMOTOGA MARITIMA RUVB T158V
1iqp	Crystal Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus
1ixr	RuvA-RuvB complex
1ixs	Structure of RuvB complexed with RuvA domain III
1ixz	Crystal structure of the FtsH ATPase domain from Thermus thermophilus
1iy0	Crystal structure of the FtsH ATPase domain with AMP-PNP from Thermus thermophilus
1iy1	Crystal structure of the FtsH ATPase domain with ADP from Thermus thermophilus
1iy2	Crystal structure of the FtsH ATPase domain from Thermus thermophilus
1j7k	THERMOTOGA MARITIMA RUVB P216G MUTANT
1j8m	Signal Recognition Particle conserved GTPase domain from A. ambivalens
1j8y	Signal Recognition Particle conserved GTPase domain from A. ambivalens T112A mutant
1jbk	Crystal Structure of the First Nucelotide Binding Domain of ClpB
1ji0	Crystal Structure Analysis of the ABC transporter from Thermotoga maritima
1jj7	Crystal Structure of the C-terminal ATPase domain of human TAP1
1jpj	GMPPNP Complex of SRP GTPase NG Domain
1jpn	GMPPNP Complex of SRP GTPase NG Domain
1jr3	Crystal Structure of the Processivity Clamp Loader Gamma Complex of E. coli DNA Polymerase III
1kmh	Crystal Structure of spinach chloroplast F1-ATPase complexed with tentoxin
1ksf	Crystal Structure of ClpA, an HSP100 chaperone and regulator of ClpAP protease: Structural basis of differences in Function of the Two AAA+ ATPase domains
1kyi	HslUV (H. influenzae)-NLVS Vinyl Sulfone Inhibitor Complex
1l2t	Dimeric Structure of MJ0796, a Bacterial ABC Transporter Cassette
1l7v	Bacterial ABC Transporter Involved in B12 Uptake
1l8q	CRYSTAL STRUCTURE OF DNA REPLICATION INITIATION FACTOR
1ls1	T. aquaticus Ffh NG Domain at 1.1A Resolution
1lv7	Crystal Structure of the AAA domain of FtsH
1mab	RAT LIVER F1-ATPASE
1mo3	RECA-ADP COMPLEX
1mo4	RECA-ATP-GAMMA-S COMPLEX
1mo5	RECA-ATP-GAMMA-S-MG COMPLEX
1mo6	RECA-DATP-MG COMPLEX
1mt0	ATP-binding domain of haemolysin B from Escherichia coli
1mv5	Crystal structure of LmrA ATP-binding domain
1n03	Model for Active RecA Filament
1n0w	Crystal structure of a RAD51-BRCA2 BRC repeat complex
1nbm	THE STRUCTURE OF BOVINE F1-ATPASE COVALENTLY INHIBITED WITH 4-CHLORO-7-NITROBENZOFURAZAN
1ng1	N AND GTPASE DOMAINS OF THE SIGNAL SEQUENCE RECOGNITION PROTEIN FFH FROM THERMUS AQUATICUS
1njf	Nucleotide bound form of an isolated E. coli clamp loader gamma subunit
1njg	Nucleotide-free form of an Isolated E. coli Clamp Loader Gamma Subunit
1nlf	Crystal Structure of DNA Helicase RepA in complex with sulfate at 1.95 A resolution
1nsf	D2 HEXAMERIZATION DOMAIN OF N-ETHYLMALEIMIDE SENSITIVE FACTOR (NSF)
1ny5	Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state
1ny6	Crystal structure of sigm54 activator (AAA+ ATPase) in the active state
1o87	A new MgGDP complex of the Ffh NG domain
1ofh	Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae)
1ofi	Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae)
1ohh	BOVINE MITOCHONDRIAL F1-ATPASE complexed with the inhibitor protein IF1
1ojl	Crystal structure of a sigma54-activator suggests the mechanism for the conformational switch necessary for sigma54 binding
1okk	HOMO-HETERODIMERIC COMPLEX OF THE SRP GTPASES
1olo	Hexameric Replicative DNA Helicase RepA from Plasmid RSF1010 - Cubic Crystal Structure
1oxs	Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
1oxt	Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
1oxu	Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
1oxv	Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
1oxx	Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus
1p9r	Crystal Structure of Vibrio cholerae putative NTPase EpsE
1p9w	Crystal Structure of Vibrio cholerae putative NTPase EpsE
1pv4	X-ray crystal structure of the Rho transcription termination factor in complex with single stranded DNA
1pvo	X-ray crystal structure of Rho transcription termination factor in complex with ssRNA substrate and ANPPNP
1pzn	Rad51 (RadA)
1q12	Crystal Structure of the ATP-bound E. coli MalK
1q1b	Crystal structure of E. coli MalK in the nucleotide-free form
1q1e	The ATPase component of E. coli maltose transporter (MalK) in the nucleotide-free form
1q3h	mouse CFTR NBD1 with AMP.PNP
1qo1	Molecular Architecture of the Rotary Motor in ATP Synthase from Yeast Mitochondria
1qvr	Crystal Structure Analysis of ClpB
1qzw	Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication
1qzx	Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication
1r0w	Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) apo
1r0x	Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ATP
1r0y	Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ADP
1r0z	Phosphorylated Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ATP
1r10	Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ATP, I4122 space group
1r6b	High resolution crystal structure of ClpA
1r7r	The crystal structure of murine p97/VCP at 3.6A
1rea	STRUCTURE OF THE RECA PROTEIN-ADP COMPLEX
1rj9	Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)
1ry1	Structure of the signal recognition particle interacting with the elongation-arrested ribosome
1s3s	Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C
1sgw	Putative ABC transporter (ATP-binding protein) from Pyrococcus furiosus Pfu-867808-001
1sky	CRYSTAL STRUCTURE OF THE NUCLEOTIDE FREE ALPHA3BETA3 SUB-COMPLEX OF F1-ATPASE FROM THE THERMOPHILIC BACILLUS PS3
1sxj	Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
1szp	A Crystal Structure of the Rad51 Filament
1t4g	ATPase in complex with AMP-PNP
1u94	Crystal Structure of E. Coli RecA in a Compressed Helical Filament Form 2
1u98	""Crystal Structure of E. coli RecA in a Compressed Helical Filament Form3""
1u99	""Crystal Structures of E. coli RecA in a Compressed Helical Filament Form 4""
1ubc	Structure of Reca Protein
1ube	MsRecA-ADP Complex
1ubf	MsREcA-ATPgS complex
1ubg	MsREcA-dATP complex
1um8	Crystal structure of helicobacter pylori ClpX
1v43	Crystal Structure of ATPase subunit of ABC Sugar Transporter
1v5w	Crystal structure of the human Dmc1 protein
1vci	Crystal structure of the ATP-binding cassette of multisugar transporter from Pyrococcus horikoshii OT3 complexed with ATP
1vdz	Crystal structure of A-type ATPase catalytic subunit A from Pyrococcus horikoshii OT3
1vma	Crystal structure of Cell division protein ftsY (TM0570) from Thermotoga maritima at 1.60 A resolution
1vpl	Crystal structure of ABC transporter ATP-binding protein (TM0544) from Thermotoga maritima at 2.10 A resolution
1w0j	Beryllium fluoride inhibited bovine F1-ATPase
1w0k	Beryllium fluoride inhibited bovine F1-ATPase
1w36	RecBCD:DNA complex
1xef	Crystal structure of the ATP/Mg2+ bound composite dimer of HlyB-NBD
1xf9	Structure of NBD1 from murine CFTR- F508S mutant
1xfa	Structure of NBD1 from murine CFTR- F508R mutant
1xmi	Crystal structure of human F508A NBD1 domain with ATP
1xmj	Crystal structure of human deltaF508 human NBD1 domain with ATP
1xms	""E. Coli RecA in complex with MnAMP-PNP""
1xmv	""E. Coli RecA in complex with MgADP""
1xp8	"Deinococcus radiodurans RecA in complex with ATP-gamma-S"
1xpo	Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin
1xpr	Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-formylbicyclomycin (FB)
1xpu	Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-(3-formylphenylsulfanyl)-dihydrobicyclomycin (FPDB)
1xu4	ATPASE IN COMPLEX WITH AMP-PNP, MAGNESIUM AND POTASSIUM CO-F
1xwi	Crystal Structure of VPS4B
1xxh	ATPgS Bound E. Coli Clamp Loader Complex
1xxi	ADP Bound E. coli Clamp Loader Complex
1ye8	Crystal Structure of THEP1 from the hyperthermophile Aquifex aeolicus
1yqt	RNase-L Inhibitor
1yr6	PAB0955 crystal structure : a GTPase in Apo form from Pyrococcus abyssi
1yr7	PAB0955 crystal structure : a GTPase in GTP-gamma-S bound form from Pyrococcus abyssi
1yr8	PAB0955 crystal structure : a GTPase in GTP bound form from Pyrococcus abyssi
1yr9	PAB0955 crystal structure : a GTPase in GDP and PO4 bound form from Pyrococcus abyssi
1yra	PAB0955 crystal structure : a GTPase in GDP bound form from Pyrococcus abyssi
1yrb	PAB0955 crystal structure : a GTPase in GDP and Mg bound form from Pyrococcus abyssi
1yyf	Correction of X-ray Intensities from an HslV-HslU co-crystal containing lattice translocation defects
1z47	Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius
1zu4	Crystal structure of FtsY from Mycoplasma mycoides- space group P21212
1zu5	Crystal structure of FtsY from Mycoplasma mycoides- space group H32
2awn	Crystal structure of the ADP-Mg-bound E. Coli MALK (Crystallized with ATP-Mg)
2awo	Crystal structure of the ADP-Mg-bound E. Coli MALK (Crystallized with ADP-Mg)
2b21	RADA Recombinase in complex with AMPPNP at pH 6.0
2bbo	Human NBD1 with Phe508
2bbs	Human deltaF508 NBD1 with three solubilizing mutations
2bbt	Human deltaF508 NBD1 with two solublizing mutations.
2bjv	Crystal Structure of PspF(1-275) R168A mutant
2bjw	PspF AAA domain
2bke	Conformational Flexibility Revealed by the Crystal Structure of a Crenarchaeal RadA
2c03	GDP COMPLEX OF SRP GTPASE FFH NG DOMAIN
2c04	GMPPCP complex of SRP GTPase Ffh NG Domain at ultra-high resolution
2c96	Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF
2c98	Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF
2c99	Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF
2c9c	Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF
2c9o	3D Structure of the human RuvB-like helicase RuvBL1
2cbz	Structure of the human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1
2ce7	EDTA treated
2cea	wildtype
2chg	Replication Factor C domains 1 and 2
2chq	Replication Factor C ADPNP complex
2chv	Replication Factor C ADPNP complex
2ck3	Azide inhibited bovine F1-ATPase
2cnw	GDPALF4 complex of the SRP GTPases Ffh and FtsY
2d3w	Crystal Structure of Escherichia coli SufC, an ATPase compenent of the SUF iron-sulfur cluster assembly machinery
2d62	Crystal structure of multiple sugar binding transport ATP-binding protein
2dfl	Crystal structure of left-handed RadA filament
2dhr	Whole cytosolic region of ATP-dependent metalloprotease FtsH (G399L)
2dpy	Crystal structure of the flagellar type III ATPase FliI
2dr3	Crystal Structure of RecA superfamily ATPase PH0284 from Pyrococcus horikoshii OT3
2ewv	Crystal Structure of the Pilus Retraction Motor PilT and Bound ADP
2eww	Crystal Structure of the Pilus Retraction Motor PilT and Bound ATP
2eyu	The Crystal Structure of the C-terminal Domain of Aquifex aeolicus PilT
2f1h	RECOMBINASE IN COMPLEX WITH AMP-PNP and Potassium
2f1i	Recombinase in Complex with AMP-PNP
2f1j	Recombinase in Complex with ADP
2f43	Rat liver F1-ATPase
2ff7	The ABC-ATPase of the ABC-transporter HlyB in the ADP bound state
2ffa	Crystal structure of ABC-ATPase H662A of the ABC-transporter HlyB in complex with ADP
2ffb	The crystal structure of the HlyB-NBD E631Q mutant in complex with ADP
2ffh	THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS
2fgj	Crystal structure of the ABC-cassette H662A mutant of HlyB with bound ATP
2fgk	Crystal structure of the ABC-cassette E631Q mutant of HlyB with bound ATP
2fpk	RadA recombinase in complex with ADP
2fpl	RadA recombinase in complex with AMP-PNP and low concentration of K+
2fpm	RadA recombinase in complex with AMP-PNP and high concentration of K+
2g88	MSRECA-dATP COMPLEX
2gdj	Delta-62 RADA recombinase in complex with AMP-PNP and magnesium
2ghi	Crystal Structure of Plasmodium yoelii Multidrug Resistance Protein 2
2gsz	Structure of A. aeolicus PilT with 6 monomers per asymmetric unit
2hcb	Structure of AMPPCP-bound DnaA from Aquifex aeolicus
2hld	Crystal structure of yeast mitochondrial F1-ATPase
2ht1	The closed ring structure of the Rho transcription termination factor in complex with nucleic acid in the motor domains
2hyd	Multidrug ABC transporter SAV1866
2i1q	RadA Recombinase in complex with Calcium
2ihy	Structure of the Staphylococcus aureus putative ATPase subunit of an ATP-binding cassette (ABC) transporter
2it1	Structure of PH0203 protein from Pyrococcus horikoshii
2iw3	Elongation Factor 3 in complex with ADP
2iwh	Structure of yeast Elongation Factor 3 in complex with ADPNP
2ix3	Structure of yeast Elongation Factor 3
2ix8	Model for eEF3 bound to an 80S ribosome
2ixe	Crystal structure of the ATPase domain of TAP1 with ATP (D645N mutant)
2ixf	Crystal structure of the ATPase domain of TAP1 with ATP (D645Q, Q678H mutant)
2ixg	Crystal structure of the ATPase domain of TAP1 with ATP (S621A, G622V, D645N mutant)
2iy3	Structure of the E. Coli Signal Regognition Particle
2iyl	Structure of an FtsY:GDP complex
2j28	Model of E. coli SRP bound to 70S RNCs
2j37	Model of Mammalian SRP bound to 80s RNCs
2j45	Water structure of T. Aquaticus Ffh NG Domain At 1.1A Resolution
2j46	Water structure of T. Aquaticus Ffh NG Domain At 1.1A Resolution
2j7p	GMPPNP-stabilized NG domain complex of the SRP GTPases Ffh and FtsY
2jdi	Ground state structure of F1-ATPase from bovine heart mitochondria ( Bovine F1-ATPase crystallised in the absence of azide)
2jiz	The Structures of F1-ATPase inhibited by resveratrol, piceatannol and quercetin.
2jj1	The Structure of F1-ATPase inhibited by piceatannol.
2jj2	The Structure of F1-ATPase inhibited by quercetin.
2ng1	N AND GTPASE DOMAINS OF THE SIGNAL SEQUENCE RECOGNITION PROTEIN FFH FROM THERMUS AQUATICUS
2nq2	An inward-facing conformation of a putative metal-chelate type ABC transporter.
2o5v	Recombination mediator RecF
2obl	Structural and biochemical analysis of a prototypical ATPase from the type III secretion system of pathogenic bacteria
2obm	Structural and biochemical analysis of a prototypical ATPase from the type III secretion system of pathogenic bacteria
2odn	MSRECA-dATP complex
2odw	MSrecA-ATP-GAMA-S complex
2oe2	MSrecA-native-low humidity 95%
2oep	MSrecA-ADP-complex
2oes	MSrecA-native-SSB
2ofo	MSrecA-native
2og2	Crystal structure of chloroplast FtsY from Arabidopsis thaliana
2olj	ABC Protein ArtP in complex with ADP/Mg2+
2olk	ABC Protein ArtP in complex with ADP-beta-S
2onj	Structure of the multidrug ABC transporter Sav1866 from S. aureus in complex with AMP-PNP
2onk	ABC transporter ModBC in complex with its binding protein ModA
2ouk	ABC Protein ArtP in complex with Sulphate
2oxr	PAB0955 crystal structure : a GTPase in GDP and Mg bound form from Pyrococcus abyssi (after GTP hydrolysis)
2p65	Crystal Structure of the first nucleotide binding domain of chaperone ClpB1, putative, (Pv089580) from Plasmodium Vivax
2pcj	Crystal structure of ABC transporter (aq_297) From Aquifex Aeolicus VF5
2pcl	Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5
2pjz	The crystal structure of putative Cobalt transport ATP-binding protein (cbiO-2), ST1066
2pmk	Crystal structures of an isolated ABC-ATPase in complex with TNP-ADP
2pze	Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer
2pzf	Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508
2pzg	Minimal human CFTR first nucleotide binding domain as a monomer
2q0h	ABC Protein ArtP in complex with ADP/Mg2+, ATP-gamma-S hydrolyzed
2q9a	Structure of Apo FTSY
2q9b	Structure of FTSY:GMPPNP Complex
2q9c	Structure of FTSY:GMPPNP with MGCL Complex
2qby	Crystal structure of a heterodimer of Cdc6/Orc1 initiators bound to origin DNA (from S. solfataricus)
2qe7	Crystal structure of the f1-atpase from the thermoalkaliphilic bacterium bacillus sp. ta2.a1
2qi9	ABC-transporter BtuCD in complex with its periplasmic binding protein BtuF
2qp9	Crystal Structure of S.cerevisiae Vps4
2qpa	Crystal Structure of S.cerevisiae Vps4 in the presence of ADP
2qy9	Structure of the NG+1 construct of the E. coli SRP receptor FtsY
2qz4	Human paraplegin, AAA domain in complex with ADP
2r62	Crystal structure of Helicobacter pylori ATP dependent protease, FtsH
2r65	Crystal structure of Helicobacter pylori ATP dependent protease, FtsH ADP complex
2r6a	Crystal Form BH1
2r6c	Crystal Form BH2
2r6d	Crystal Form B1
2r6e	Crystal Form B2
2r6f	Crystal Structure of Bacillus stearothermophilus UvrA
2r6g	The Crystal Structure of the E. coli Maltose Transporter
2reb	THE STRUCTURE OF THE E. COLI RECA PROTEIN MONOMER AND POLYMER
2rec	RECA HEXAMER MODEL, ELECTRON MICROSCOPY
2rko	Crystal Structure of the Vps4p-dimer
2v1u	STRUCTURE OF THE AEROPYRUM PERNIX ORC1 PROTEIN IN COMPLEX WITH DNA
2v3c	Crystal structure of the SRP54-SRP19-7S.S SRP RNA complex of M. jannaschii
2v7q	The structure of F1-ATPase inhibited by I1-60HIS, a monomeric form of the inhibitor protein, IF1.
2vii	PspF1-275-Mg-AMP
2vye	Crystal Structure of the DnaC-ssDNA complex
2vyf	Crystal Structure of the DnaC
2w0m	Crystal Structure of sso2452 from Sulfolobus solfataricus P2
2w58	Crystal Structure of the DnaI
2w6e	Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration:hydration state 1.
2w6f	Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration: Hydration State 2.
2w6g	Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration: Hydration State 3.
2w6h	Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration: Hydration State 4A.
2w6i	Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration: Hydration State 4B.
2w6j	Low resolution structures of bovine mitochondrial F1-ATPase during controlled dehydration: Hydration State 5.
2wpd	The Mg.ADP inhibited state of the yeast F1c10 ATP synthase
2wss	The structure of the membrane extrinsic region of bovine ATP synthase
2www	Crystal Structure of Methylmalonic Acidemia Type A Protein
2x31	Modelling of the complex between subunits BchI and BchD of magnesium chelatase based on single-particle cryo-EM reconstruction at 7.5 ang
2x8a	Human Nuclear Valosin containing protein Like (NVL), C-terminal AAA- ATPase domain
2xkv	Atomic Model of the SRP-FtsY Early Conformation
2xnd	Crystal structure of bovine F1-c8 sub-complex of ATP Synthase
2xok	Refined structure of yeast F1c10 ATPase complex to 3 A resolution
2xsz	The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II
2xxa	The Crystal Structure of the Signal Recognition Particle (SRP) in Complex with its Receptor(SR)
2xzl	Upf1-RNA complex
2yhs	Structure of the E. coli SRP receptor FtsY
2ykg	Structural insights into RNA recognition by RIG-I
2yyz	Crystal structure of Sugar ABC transporter, ATP-binding protein
2yz2	Crystal structure of the ABC transporter in the cobalt transport system
2z43	Structure of a twinned crystal of RadA
2z4r	Crystal structure of domain III from the Thermotoga maritima replication initiation protein DnaA
2z4s	Crystal structure of domain III from the Thermotoga maritima replication initiation protein DnaA
2zam	Crystal structure of mouse SKD1/VPS4B apo-form
2zan	Crystal structure of mouse SKD1/VPS4B ATP-form
2zao	Crystal structure of mouse SKD1/VPS4B ADP-form
2zjb	Crystal structure of the human Dmc1-M200V polymorphic variant
2zr0	MSRECA-Q196E mutant
2zr7	Msreca native form II'
2zr9	MsRecA Q196E dATP form IV
2zra	MsRecA Q196E ATPgS
2zrb	MsRecA Q196E Form II'
2zrc	MsRecA Q196N Form IV
2zrd	MsRecA Q196N ADP form IV
2zre	MsRecA Q196N ATPgS form IV
2zrf	MsRecA Q196N dATP form IV
2zrg	MsRecA Q196N dATP form II'
2zrh	MsRecA Q196A form IV
2zri	MsRecA Q196A ADP form IV
2zrj	MsRecA Q196A ATPgS form IV
2zrk	MsRecA Q196A dATP form IV
2zrl	MsRecA Q196A dATP FORM II'
2zrm	MsRecA dATP form IV
2zrn	MsRecA Form IV
2zro	MsRecA ADP form IV
2zrp	MsRecA dATP form II'
2zts	Crystal structure of KaiC-like protein PH0186 from hyperthermophilic archaea Pyrococcus horikoshii OT3
2zu0	Crystal structure of SufC-SufD complex involved in the iron-sulfur cluster biosynthesis
2zub	Left handed RadA
2zuc	Crystal structure of left-handed RadA filament
2zud	Crystal Structure of Left-handed RadA Filament
3asy	ligand-free structure of uridine kinase from thermus thermophilus HB8
3asz	CMP-complex structure of uridine kinase from Thermus thermophilus HB8
3aux	Crystal structure of Rad50 bound to ADP
3auy	Crystal structure of Rad50 bound to ADP
3av0	Crystal structure of Mre11-Rad50 bound to ATP S
3b5j	Crystal Structures of the S504A Mutant of an Isolated ABC-ATPase in Complex with TNP-ADP
3b5w	Crystal Structure of Eschericia coli MsbA
3b5x	Crystal Structure of MsbA from Vibrio cholerae
3b5y	Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP
3b5z	Crystal Structure of MsbA from Salmonella typhimurium with ADP Vanadate
3b60	Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form
3b9p	Spastin
3b9q	The crystal structure of cpFtsY from Arabidopsis thaliana
3bk7	Structure of the complete ABCE1/RNAase-L Inhibitor protein from Pyrococcus abysii
3c41	ABC protein ArtP in complex with AMP-PNP/Mg2+
3c4j	ABC protein ArtP in complex with ATP-gamma-S
3cf0	Structure of D2 subdomain of P97/VCP in complex with ADP
3cf1	Structure of P97/vcp in complex with ADP/ADP.alfx
3cf2	Structure of P97/vcp in complex with ADP/AMP-PNP
3cf3	Structure of P97/vcp in complex with ADP
3cmt	Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
3cmu	Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
3cmv	Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
3cmw	Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
3cmx	Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
3d31	ModBC from Methanosarcina acetivorans
3d8b	Crystal structure of human fidgetin-like protein 1 in complex with ADP
3dhw	Crystal structure of methionine importer MetNI
3dm5	Structures of SRP54 and SRP19, the two proteins assembling the ribonucleic core of the Signal Recognition Particle from the archaeon Pyrococcus furiosus.
3dm9	Structures and Conformations in Solution of the Signal Recognition Particle Receptor from the archaeon Pyrococcus furiosus
3dmd	Structures and Conformations in Solution of the Signal Recognition Particle Receptor from the archaeon Pyrococcus furiosus
3dzd	Crystal structure of sigma54 activator NTRC4 in the inactive state
3e1s	Structure of an N-terminal truncation of Deinococcus radiodurans RecD2
3e70	Structures and conformations in solution of the Signal Recognition Particle Receptor from the Archaeon Pyrococcus Furiosus
3ec2	Crystal structure of the DnaC helicase loader
3ecc	Crystal structure of the DnaC helicase loader in complex with ADP-BeF3
3eie	Crystal Structure of S.cerevisiae Vps4 in the SO4-bound state
3eih	Crystal structure of S.cerevisiae Vps4 in the presence of ATPgammaS
3etl	RadA recombinase from Methanococcus maripaludis in complex with AMPPNP
3ew9	RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and potassium ions
3ewa	RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions
3f9v	Crystal Structure Of A Near Full-Length Archaeal MCM: Functional Insights For An AAA+ Hexameric Helicase
3fh6	Crystal structure of the resting state maltose transporter from E. coli
3fks	Yeast F1 ATPase in the absence of bound nucleotides
3fvq	Crystal structure of the nucleotide binding domain FbpC complexed with ATP
3fyh	Recombinase in complex with ADP and metatungstate
3g5u	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
3g60	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
3g61	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
3gd7	Crystal structure of human NBD2 complexed with N6-Phenylethyl-ATP (P-ATP)
3gfo	Structure of cbiO1 from clostridium perfringens: Part of the ABC transporter complex cbiONQ.
3glf	Crystal Structure of the Ecoli Clamp Loader Bound to Primer-Template DNA
3glg	Crystal Structure of a Mutant (gammaT157A) E. coli Clamp Loader Bound to Primer-Template DNA
3glh	Crystal Structure of the E. coli clamp loader bound to Psi Peptide
3gli	Crystal Structure of the E. coli clamp loader bound to Primer-Template DNA and Psi Peptide
3gp8	Crystal structure of the binary complex of RecD2 with DNA
3gpl	Crystal structure of the ternary complex of RecD2 with DNA and ADPNP
3h4m	AAA ATPase domain of the proteasome- activating nucleotidase
3hr8	Crystal Structure of Thermotoga maritima RecA
3hte	Crystal structure of nucleotide-free hexameric ClpX
3hu1	Structure of p97 N-D1 R95G mutant in complex with ATPgS
3hu2	Structure of p97 N-D1 R86A mutant in complex with ATPgS
3hu3	Structure of p97 N-D1 R155H mutant in complex with ATPgS
3hws	Crystal structure of nucleotide-bound hexameric ClpX
3i4l	Structural characterization for the nucleotide binding ability of subunit A with AMP-PNP of the A1AO ATP synthase
3i72	Structural characterization for the nucleotide binding ability of subunit A with SO4 of the A1AO ATP synthase
3i73	Structural characterization for the nucleotide binding ability of subunit A with ADP of the A1AO ATP synthase
3ice	Rho transcription termination factor bound to RNA and ADP-BeF3
3ikj	Structural characterization for the nucleotide binding ability of subunit A mutant S238A of the A1AO ATP synthase
3j15	Model of ribosome-bound archaeal Pelota and ABCE1
3j16	Models of ribosome-bound Dom34p and Rli1p and their ribosomal binding partners
3j3r	Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
3j3s	Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
3j3t	Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
3j3u	Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
3j5s	EttA binds to ribosome exit site and regulates translation by restricting ribosome and tRNA dynamics
3j67	Structural mechanism of the dynein powerstroke (post-powerstroke state)
3j68	Structural mechanism of the dynein powerstroke (pre-powerstroke state)
3j94	3J94
3j95	3J95
3j96	3J96
3j97	3J97
3j98	3J98
3j99	3J99
3j9t	3J9T
3j9u	3J9U
3j9v	3J9V
3ja8	3JA8
3jag	3JAG
3jah	3JAH
3jai	3JAI
3jaj	3JAJ
3jan	3JAN
3jc5	3JC5
3jc6	3JC6
3jc7	3JC7
3jc8	3JC8
3jcm	3JCM
3jco	3JCO
3jcp	3JCP
3jcr	3JCR
3jvu	Crystal structure of unliganded P. aeruginosa PilT
3jvv	Crystal Structure of P. aeruginosa PilT with bound AMP-PCP
3k1j	Crystal structure of Lon protease from Thermococcus onnurineus NA1
3k70	Crystal structure of the complete initiation complex of RecBCD
3kds	apo-FtsH crystal structure
3kl4	Recognition of a signal peptide by the signal recognition particle
3l0o	Structure of RNA-free Rho transcription termination factor from Thermotoga maritima
3lda	Yeast Rad51 H352Y Filament Interface Mutant
3m0e	Crystal structure of the ATP-bound state of Walker B mutant of NtrC1 ATPase domain
3m4y	Structural characterization of the subunit A mutant P235A of the A-ATP synthase
3m6a	Crystal structure of Bacillus subtilis Lon C-terminal domain
3mfy	Structural characterization of the subunit A mutant F236A of the A-ATP synthase from Pyrococcus horikoshii
3nbx	Crystal structure of E. coli RavA (Regulatory ATPase variant A) in complex with ADP
3ndb	Crystal structure of a signal sequence bound to the signal recognition particle
3ng1	N AND GTPASE DOMAINS OF THE SIGNAL SEQUENCE RECOGNITION PROTEIN FFH FROM THERMUS AQUATICUS
3nh6	Nucleotide Binding Domain of human ABCB6 (apo structure)
3nh9	Nucleotide Binding Domain of Human ABCB6 (ATP bound structure)
3nha	Nucleotide Binding Domain of Human ABCB6 (ADP Mg bound structure)
3nhb	Nucleotide Binding Domain of Human ABCB6 (ADP bound structure)
3ntu	RADA RECOMBINASE D302K MUTANT IN COMPLEX with AMP-PNP
3nxs	Crystal structure of LAO/AO transport system from Mycobacterium smegmatis bound to GDP
3oaa	Structure of the E.coli F1-ATP synthase inhibited by subunit Epsilon
3oe7	Structure of four mutant forms of yeast f1 ATPase: gamma-I270T
3oee	Structure of four mutant forms of yeast F1 ATPase: alpha-F405S
3oeh	Structure of four mutant forms of yeast F1 ATPase: beta-V279F
3ofn	Structure of four mutant forms of yeast F1 ATPase: alpha-N67I
3oiy	Helicase domain of reverse gyrase from Thermotoga maritima
3ozx	Crystal structure of ABCE1 of Sulfolubus solfataricus (-FeS domain)
3p20	Crystal structure of vanadate bound subunit A of the A1AO ATP synthase
3p4x	Helicase domain of reverse gyrase from Thermotoga maritima
3p4y	Helicase domain of reverse gyrase from Thermotoga maritima - P2 form
3pfi	2.7 Angstrom resolution crystal structure of a probable holliday junction DNA helicase (ruvB) from Campylobacter jejuni subsp. jejuni NCTC 11168 in complex with adenosine-5'-diphosphate
3pih	T. maritima UvrA in complex with fluorescein-modified DNA
3puv	Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-VO4
3puw	Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-AlF4
3pux	Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-BeF3
3puy	Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to AMP-PNP after crystal soaking of the pretranslocation state
3puz	Crystal Structure of a pre-translocation state MBP-Maltose transporter complex bound to AMP-PNP
3pv0	Crystal Structure of a pre-translocation state MBP-Maltose transporter complex without nucleotide
3pvs	Structure and biochemical activities of Escherichia coli MgsA
3pxg	Structure of MecA121 and ClpC1-485 complex
3pxi	Structure of MecA108:ClpC
3qf4	Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
3qf7	The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair
3qg5	The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair
3qjy	Crystal structure of P-loop G234A mutant of subunit A of the A1AO ATP synthase
3qkt	Rad50 ABC-ATPase with adjacent coiled-coil region in complex with AMP-PNP
3qku	Mre11 Rad50 binding domain in complex with Rad50 and AMP-PNP
3qmz	Crystal structure of the cytoplasmic dynein heavy chain motor domain
3r8f	Protein-DNA complex
3rlf	Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to MgAMPPNP
3sdz	Structural characterization of the subunit A mutant F427W of the A-ATP synthase from Pyrococcus horikoshii
3se0	Structural characterization of the subunit A mutant F508W of the A-ATP synthase from Pyrococcus horikoshii
3si7	The crystal structure of the NBD1 domain of the mouse CFTR protein, deltaF508 mutant
3syk	Crystal structure of the AAA+ protein CbbX, selenomethionine structure
3syl	Crystal structure of the AAA+ protein CbbX, native structure
3tif	Dimeric structure of a post-hydrolysis state of the ATP-binding cassette MJ0796 bound to ADP and Pi
3tk1	Crystal structure of a MeaB and Rv1496 ortholog from Mycobacterium thermoresistible bound to GDP
3tui	Inward facing conformations of the MetNI methionine ABC transporter: CY5 native crystal form
3tuj	Inward facing conformations of the MetNI methionine ABC transporter: DM crystal form
3tuz	Inward facing conformations of the MetNI methionine ABC transporter: CY5 SeMet soak crystal form
3u5z	Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog
3u60	Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog
3u61	Structure of T4 Bacteriophage Clamp Loader Bound To Closed Clamp, DNA and ATP Analog and ADP
3uk6	Crystal Structure of the Tip48 (Tip49b) hexamer
3upu	Crystal structure of the T4 Phage SF1B Helicase Dda
3uwx	Crystal structure of UvrA-UvrB complex
3ux8	Crystal structure of UvrA
3vfd	Human spastin AAA domain
3vkg	X-ray structure of an MTBD truncation mutant of dynein motor domain
3vkh	X-ray structure of a functional full-length dynein motor domain
3vx4	Crystal Structure of the Nucleotide-Binding Domain of S. mutans ComA, a Bifunctional ATP-binding Cassette Transporter Involved in the Quorum-sensing Pathway
3w34	Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates
3w8r	Mutant structure of Thermus thermophilus HB8 uridine-cytidine kinase
3whk	Crystal structure of PAN-Rpt5C chimera
3whl	Crystal structure of Nas2 N-terminal domain complexed with PAN-Rpt5C chimera
3wme	Crystal structure of an inward-facing eukaryotic ABC multidrug transporter
3wmf	Crystal structure of an inward-facing eukaryotic ABC multitrug transporter G277V/A278V/A279V mutant
3wmg	Crystal structure of an inward-facing eukaryotic ABC multidrug transporter G277V/A278V/A279V mutant in complex with an cyclic peptide inhibitor, aCAP
3zd6	Snapshot 1 of RIG-I scanning on RNA duplex
3zd7	Snapshot 3 of RIG-I scanning on RNA duplex
3zdq	STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 ( NUCLEOTIDE-FREE FORM)
3zgx	Crystal structure of the kleisin-N SMC interface in prokaryotic condensin
3zia	The structure of F1-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF1
3zn8	Structural Basis of Signal Sequence Surveillance and Selection by the SRP-SR Complex
3zry	Rotor architecture in the F(1)-c(10)-ring complex of the yeast F-ATP synthase
3zuh	Negative stain EM Map of the AAA protein CbbX, a red-type Rubisco activase from R. sphaeroides
4a6p	RadA C-terminal ATPase domain from Pyrococcus furiosus
4a6x	RadA C-terminal ATPase domain from Pyrococcus furiosus bound to ATP
4a82	Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966.
4ag5	Structure of VirB4 of Thermoanaerobacter pseudethanolicus
4ag6	Structure of VirB4 of Thermoanaerobacter pseudethanolicus
4ai6	Dynein Motor Domain - ADP complex
4ak9	Structure of chloroplast FtsY from Physcomitrella patens
4akg	Dynein Motor Domain - ATP complex
4akh	Dynein Motor Domain - AMPPNP complex
4aki	Dynein Motor Domain - LuAc derivative
4asu	F1-ATPase in which all three catalytic sites contain bound nucleotide, with magnesium ion released in the Empty site
4ay2	Capturing 5' tri-phosphorylated RNA duplex by RIG-I
4ayt	STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10
4ayw	STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM)
4ayx	STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (ROD FORM B)
4b2i	Humanised monomeric RadA in complex with indazole
4b2l	Humanised monomeric RadA in complex with L-methylester tryptophan
4b2p	RadA C-terminal ATPase domain from Pyrococcus furiosus bound to GTP
4b2q	Model of the yeast F1Fo-ATP synthase dimer based on subtomogram average
4b32	Humanised monomeric RadA in complex with napht-1-ol
4b33	Humanised monomeric RadA in complex with napht-2-ol
4b34	Humanised monomeric RadA in complex with 2-amino benzothiazole
4b35	Humanised monomeric RadA in complex with 4-methylester indole
4b3b	Humanised monomeric RadA in complex with FHTA tetrapeptide
4b3c	Humanised monomeric RadA in complex with 5-hydroxy indole
4b3d	Humanised monomeric RadA in complex with 5-methyl indole
4b3f	crystal structure of Ighmbp2 helicase
4b3g	crystal structure of Ighmbp2 helicase in complex with RNA
4bgd	Crystal structure of Brr2 in complex with the Jab1/MPN domain of Prp8
4bpb	STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY RIG-I
4bs1	MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
4bt0	MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
4bt1	MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
4c3z	4C3Z
4c7o	The structural basis of FtsY recruitment and GTPase activation by SRP RNA
4ciu	Crystal structure of E. coli ClpB
4cr2	Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
4cr3	Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
4cr4	Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
4crm	4CRM
4d2q	4D2Q
4d2u	4D2U
4d2x	4D2X
4d6p	4D6P
4d80	4D80
4d81	4D81
4d82	4D82
4dbl	Crystal structure of E159Q mutant of BtuCDF
4dc9	Hexameric ring of Methanococcus voltae RadA
4ddt	Thermotoga maritima reverse gyrase, C2 FORM 2
4ddu	Thermotoga maritima reverse gyrase, C2 FORM 1
4ddv	Thermotoga maritima reverse gyrase, triclinic form
4ddw	Thermotoga maritima reverse gyrase, c-centered orthorhombic form
4ddx	Thermotoga maritima reverse gyrase, primitive monoclinic form
4eiw	Whole cytosolic region of atp-dependent metalloprotease FtsH (G399L)
4esv	A New Twist on the Translocation Mechanism of Helicases from the Structure of DnaB with its Substrates
4f4c	The Crystal Structure of the Multi-Drug Transporter
4f91	Brr2 Helicase Region
4f92	Brr2 Helicase Region S1087L
4f93	Brr2 Helicase Region S1087L, Mg-ATP
4fct	Crystal structure of the C-terminal domain of ClpB
4fcv	Crystal structure of the C-terminal domain of ClpB
4fcw	Crystal structure of the C-terminal domain of ClpB
4fd2	Crystal structure of the C-terminal domain of ClpB
4fdg	Crystal Structure of an Archaeal MCM Filament
4fi3	Structure of vitamin B12 transporter BtuCD-F in a nucleotide-bound state
4fin	Crystal Structure of EttA (formerly YjjK) - an E. coli ABC-type ATPase
4fwi	Crystal structure of the nucleotide-binding domain of a dipeptide ABC transporter
4g1u	X-ray structure of the bacterial heme transporter HmuUV from Yersinia pestis
4hlu	Structure of the EcfA-A' heterodimer bound to ADP
4hse	Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP
4huq	Crystal Structure of a transporter
4hyy	Filament of octameric rings of DMC1 recombinase from Homo sapiens
4hzi	Crystal structure of the Leptospira interrogans ATPase subunit of an orphan ABC transporter
4hzu	Structure of a bacterial energy-coupling factor transporter
4i34	Crystal Structure of W-W-W ClpX Hexamer
4i4l	Crystal Structure of Nucleotide-Bound W-W-W ClpX Hexamer
4i5o	Crystal Structure of W-W-R ClpX Hexamer
4i63	Crystal Structure of E-R ClpX Hexamer
4i81	Crystal Structure of ATPgS bound ClpX Hexamer
4i99	Crystal structure of the SmcHead bound to the C-winged helix domain of ScpA
4i9k	Crystal structure of symmetric W-W-W ClpX Hexamer
4jbw	Crystal structure of E. coli maltose transporter MalFGK2 in complex with its regulatory protein EIIAglc
4k8o	4K8O
4khz	Crystal structure of the maltose-binding protein/maltose transporter complex in an pre-translocation conformation bound to maltoheptaose
4ki0	Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to maltohexaose
4kit	Crystal structure of human Brr2 in complex with the Prp8 Jab1/MPN domain
4kln	Structure of p97 N-D1 A232E mutant in complex with ATPgS
4ko8	Structure of p97 N-D1 R155H mutant in complex with ATPgS
4kod	Structure of p97 N-D1 R155H mutant in complex with ADP
4ksb	Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
4ksc	Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
4ksd	Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
4ksr	Crystal Structure of the Vibrio cholerae ATPase GspE Hexamer
4kss	Crystal Structure of Vibrio cholerae ATPase GspsE Hexamer
4l15	Crystal structure of FIGL-1 AAA domain
4l16	Crystal structure of FIGL-1 AAA domain in complex with ADP
4l4u	Crystal structure of construct containing A. aeolicus NtrC1 receiver, central and DNA binding domains
4lcb	Structure of Vps4 homolog from Acidianus hospitalis
4lgm	Crystal Structure of Sulfolobus solfataricus Vps4
4lj4	ClpB NBD2 from T. thermophilus, nucleotide-free
4lj5	ClpB NBD2 from T. thermophilus in complex with ADP
4lj6	ClpB NBD2 from T. thermophilus in complex with AMPPCP
4lj7	ClpB NBD2 K601Q from T. thermophilus in complex with MANT-dADP
4lj8	ClpB NBD2 R621Q from T. thermophilus in complex with ADP
4lj9	ClpB NBD2 R621Q from T. thermophilus in complex with AMPPCP
4lja	ClpB NBD2 R621Q from T. thermophilus in complex with AMPPCP and guanidinium chloride
4lsg	Structure of Mouse P-Glycoprotein
4ly6	Nucleotide-induced asymmetry within ATPase activator ring drives s54-RNAP interaction and ATP hydrolysis
4lzz	Nucleotide-induced asymmetry within atpase activator ring drives s54-RNAP interaction and ATP hydrolysis
4m1m	Corrected Structure of Mouse P-glycoprotein
4m2s	Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR
4m2t	Corrected Structure of Mouse P-glycoprotein bound to QZ59-SSS
4m4w	Mechanistic implications for the bacterial primosome assembly of the structure of a helicase-helicase loader complex
4mki	Cobalt transporter ATP-binding subunit
4mrn	Structure of a bacterial Atm1-family ABC transporter
4mrp	Structure of a bacterial Atm1-family ABC transporter
4mrr	Structure of a bacterial Atm1-family ABC transporter
4mrs	Structure of a bacterial Atm1-family ABC transporter
4mrv	Structure of a bacterial Atm1-family ABC transporter
4myc	Structure of the mitochondrial ABC transporter, Atm1
4myh	Structure of the Glutathione bound mitochondrial ABC transporter, Atm1
4nch	Crystal Structure of Pyrococcus furiosis Rad50 L802W mutation
4nci	Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation
4ncj	Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium Flouride
4nck	Crystal Structure of Pyrococcus furiosis Rad50 R797G mutation
4nh0	4NH0
4nmn	Aquifex aeolicus replicative helicase (DnaB) complexed with ADP, at 3.3 resolution
4nph	4NPH
4on9	4ON9
4oqf	4OQF
4p31	Crystal structure of a selenomethionine derivative of E. coli LptB in complex with ADP-Magensium
4p32	Crystal structure of E. coli LptB in complex with ADP-magnesium
4p33	Crystal structure of E. coli LptB-E163Q in complex with ATP-sodium
4pht	4PHT
4pl0	4PL0
4po1	4PO1
4po8	4PO8
4po9	4PO9
4poa	4POA
4ppf	4PPF
4ppg	4PPG
4ppn	4PPN
4ppq	4PPQ
4pqf	4PQF
4pqr	4PQR
4pqy	4PQY
4pr0	4PR0
4psa	4PSA
4psk	4PSK
4psv	4PSV
4ptl	4PTL
4q4a	4Q4A
4q4h	4Q4H
4q4j	4Q4J
4q4l	Crystal structure of an ATP synthase subunit beta 1 (F1-B1) from Burkholderia thailandensis
4q7k	4Q7K
4q7l	4Q7L
4q7m	4Q7M
4q9h	4Q9H
4q9i	4Q9I
4q9j	4Q9J
4q9k	4Q9K
4q9l	4Q9L
4qc2	4QC2
4qhs	4QHS
4qht	4QHT
4qkq	4QKQ
4qnm	4QNM
4qnr	4QNR
4qos	4QOS
4r7y	4R7Y
4r9u	4R9U
4rfs	4RFS
4rh7	4RH7
4rvc	4RVC
4ry2	4RY2
4s0f	4S0F
4tqu	4TQU
4tqv	4TQV
4tsf	4TSF
4tt3	4TT3
4twz	4TWZ
4u00	4U00
4u02	4U02
4ue5	4UE5
4upb	4UPB
4uqo	4UQO
4w8f	4W8F
4w9m	4W9M
4wbs	4WBS
4wia	4WIA
4wvy	4WVY
4ww0	4WW0
4ww4	4WW4
4wz6	4WZ6
4xd7	4XD7
4xgc	4XGC
4xgu	4XGU
4xig	4XIG
4xtc	4XTC
4xwk	4XWK
4yer	4YER
4yms	4YMS
4ymt	4YMT
4ymu	4YMU
4ymv	4YMV
4ymw	4YMW
4ypl	4YPL
4ypn	4YPN
4yxw	4YXW
4z1m	4Z1M
4z8x	4Z8X
4zir	4ZIR
4zpx	4ZPX
5a5b	5A5B
5ara	5ARA
5are	5ARE
5arh	5ARH
5ari	5ARI
5awf	5AWF
5awg	5AWG
5b0o	5B0O
5b57	5B57
5b58	5B58
5bq5	5BQ5
5bw9	5BW9
5c18	5C18
5c19	5C19
5c1a	5C1A
5c1b	5C1B
5c73	5C73
5c76	5C76
5c78	5C78
5cdf	5CDF
5d3m	5D3M
5d80	5D80
5da9	5DA9
5dca	5DCA
5dgx	5DGX
5dn6	5DN6
5dny	5DNY
5do7	5DO7
5dyg	5DYG
5dyi	5DYI
5e3h	5E3H
5e7p	5E7P
5eg1	5EG1
5ep0	5EP0
5ep1	5EP1
5ep2	5EP2
5ep3	5EP3
5ep4	5EP4
5eqt	5EQT
5eum	5EUM
5exp	5EXP
5exs	5EXS
5ext	5EXT
5exx	5EXX
5f3w	5F3W
5f98	5F98
5f9f	5F9F
5f9h	5F9H
5fij	5FIJ
5fik	5FIK
5fil	5FIL
5fl3	5FL3
5fl7	5FL7
5fl8	5FL8
5fm6	5FM6
5fm7	5FM7
5fos	5FOS
5fot	5FOT
5fou	5FOU
5fov	5FOV
5fow	5FOW
5fox	5FOX
5fpk	5FPK
5ftb	5FTB
5ftc	5FTC
5ftd	5FTD
5fte	5FTE
5ftf	5FTF
5ftj	5FTJ
5ftk	5FTK
5ftl	5FTL
5ftm	5FTM
5ftn	5FTN
5g4f	5G4F
5g4g	5G4G
5gad	5GAD
5gaf	5GAF
5gag	5GAG
5gah	5GAH
5gan	5GAN
5gao	5GAO
5gap	5GAP
5gjq	5GJQ
5gjr	5GJR
5gm6	5GM6
5hkk	5HKK
5idv	5IDV
5ifs	5IFS
5ifw	5IFW
5ik2	5IK2
5j4h	5J4H
5j4k	5J4K
5j4l	5J4L
5jcs	5JCS
5jec	5JEC
5jed	5JED
5jee	5JEE
5jfg	5JFG
5ji2	5JI2
5jji	5JJI
5jjk	5JJK
5jjl	5JJL
5jrj	5JRJ
5jsz	5JSZ
5jzc	5JZC
5kdd	5KDD
5kne	5KNE
5ko2	5KO2
5kpd	5KPD
5kpi	5KPI
5kpj	5KPJ
5l3q	5L3Q
5l3r	5L3R
5l3s	5L3S
5l3v	5L3V
5l3w	5L3W
5l4g	5L4G
5l8v	5L8V
5lb2	5LB2
5lb4	5LB4
5lbi	5LBI
5ld2	5LD2
5lj5	5LJ5
5lqw	5LQW
5lqx	5LQX
5lqy	5LQY
5lqz	5LQZ
5lw7	5LW7
5lzv	5LZV
5swj	5SWJ
5swl	5SWL
5syp	5SYP
5syr	5SYR
5t0c	5T0C
5t0g	5T0G
5t0h	5T0H
5t0i	5T0I
5t0j	5T0J

Links (links to other resources describing this domain)

• PROSITE: AAA
• INTERPRO: IPR003593
• PFAM: AAA