SMART: CARP domain annotation

SKDIQIQVMGRVPTISINKTEGCHLYLSEDALDCEIVS

CARP Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product.

SMART accession number:	SM00673
Description:	-
Interpro abstract (IPR006599):	This entry represents the CARP motif, which occurs as a tandem repeat in the C-terminal of many cyclase-associated proteins (CAPs), as well as in tubulin binding cofactor C and the X-linked retinitis pigmentosa 2 protein (RP2).
Family alignment:	View or

There are 9477 CARP domains in 5087 proteins in SMART's nrdb database.

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Evolution (species in which this domain is found)
Taxonomic distribution of proteins containing CARP domain.
This tree includes only several representative species. The complete taxonomic breakdown of all proteins with CARP domain is also avaliable.

Click on the protein counts, or double click on taxonomic names to display all proteins containing CARP domain in the selected taxonomic class.
Cellular role (predicted cellular role)
Cellular role: signalling
Binding / catalysis: Proper folding of tubulin?
Structure (3D structures containing this domain)

PDB code	Main view	Title
1k4z		C-terminal Domain of Cyclase Associated Protein
1k8f		CRYSTAL STRUCTURE OF THE HUMAN C-TERMINAL CAP1-ADENYLYL CYCLASE ASSOCIATED PROTEIN
1kq5		C-terminal Domain of Cyclase Associated Protein with PRO 505 Replaced by SER (P505S)
2b0r		Crystal Structure of Cyclase-Associated Protein from Cryptosporidium parvum
2bx6		Crystal Structure of the human Retinitis Pigmentosa protein 2 (RP2)
2yuh		Solution structure of the C-terminal region in human tubulin folding cofactor C
3bh6		Crystal structure of the RP2-Arl3 complex bound to GppNHp
3bh7		Crystal structure of the RP2-Arl3 complex bound to GDP-AlF4
5aj8		5AJ8
5cya		5CYA

CARP