The domain within your query sequence starts at position 529 and ends at position 565; the E-value for the CHZ domain shown below is 1.17e-11.
REEAAEVAALDVANIISSTGRPRRRNAWNPSGEGTSP
CHZHistone chaperone domain CHZ |
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SMART accession number: | SM01082 |
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Description: | This domain is highly conserved from yeasts to humans and is part of the chaperone protein HIRIP3 in vertebrates which interacts with the H3.3 chaperone HIRA, implicated in histone replacement during transcription. N- and C- termini of Chz family members are relatively divergent but do contain similar acidic stretches rich in Glu/Asp residues, characteristic of all histone chaperones (PUBMED:17289584). |
Interpro abstract (IPR019098): | This domain is highly conserved from yeasts to humans and is part of the chaperone protein HIRIP3 in vertebrates which interacts with the H3.3 chaperone HIRA, implicated in histone replacement during transcription. N- and C- termini of Chz family members are relatively divergent but do contain similar acidic stretches rich in Glu/Asp residues, characteristic of all histone chaperones [ (PUBMED:17289584) ]. |
Family alignment: |
There are 1023 CHZ domains in 981 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
- Cellular role (predicted cellular role)
- Literature (relevant references for this domain)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)