CxxC_CXXC_SSSS Putative regulatory protein
SMART ACC:	SM000834
Description:	CxxC_CXXC_SSSS represents a region of about 41 amino acids found in a number of small proteins in a wide range of bacteria. The region usually begins with the initiator Met and contains two CxxC motifs separated by 17 amino acids. One protein in this entry has been noted as a putative regulatory protein, designated FmdB. Most proteins in this entry have a C-terminal region containing highly degenerate sequence.
InterPro ACC:	IPR013429
InterPro abstract:	This entry represents a putative zinc beta-ribbon domain of about 41 amino acids found in a number of small proteins in a wide range of bacteria. The region usually begins with the initiator Met and contains two CxxC motifs separated by 17 amino acids. One protein in this entry has been noted as a putative regulatory protein, designated FmdB [ PUBMED:8841393 … expand This entry represents a putative zinc beta-ribbon domain of about 41 amino acids found in a number of small proteins in a wide range of bacteria. The region usually begins with the initiator Met and contains two CxxC motifs separated by 17 amino acids. One protein in this entry has been noted as a putative regulatory protein, designated FmdB [ PUBMED:8841393 ]. Most proteins in this entry have a C-terminal region containing highly degenerate sequence. collapse
Family alignment:	View the Family alignment or the Alignment consensus sequence
There are 12 186 CxxC_CXXC_SSSS domains in 12 186 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing CxxC_CXXC_SSSS domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing CxxC_CXXC_SSSS domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:	Metabolic

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a CxxC_CXXC_SSSS domain which could be assigned to a KEGG orthologous group, and not all proteins containing CxxC_CXXC_SSSS domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Links to other resources describing this domain

InterPro	IPR013429
Pfam	CxxC_CxxC_SSSS