PDB code | Main view | Title | 1e9h |  | Thr 160 phosphorylated CDK2 - Human cyclin A3 complex with the inhibitor indirubin-5-sulphonate bound |
1fin |  | CYCLIN A-CYCLIN-DEPENDENT KINASE 2 COMPLEX |
1fvv |  | THE STRUCTURE OF CDK2/CYCLIN A IN COMPLEX WITH AN OXINDOLE INHIBITOR |
1gy3 |  | pCDK2/cyclin A in complex with MgADP, nitrate and peptide substrate |
1h1p |  | Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU2058 |
1h1q |  | Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6094 |
1h1r |  | Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6086 |
1h1s |  | Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6102 |
1h24 |  | CDK2/CyclinA in complex with a 9 residue recruitment peptide from E2F |
1h25 |  | CDK2/CyclinA in complex with an 11-residue recruitment peptide from E2F |
1h26 |  | CDK2/CyclinA in complex with an 11-residue recruitment peptide from p53 |
1h27 |  | CDK2/CyclinA in complex with an 11-residue recruitment peptide from p27 |
1h28 |  | CDK2/CyclinA in complex with an 11-residue recruitment peptide from p107 |
1jst |  | PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A |
1jsu |  | P27(KIP1)/CYCLIN A/CDK2 COMPLEX |
1ogu |  | STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 2-ARYLAMINO-4-CYCLOHEXYLMETHYL-5-NITROSO-6-AMINOPYRIMIDINE INHIBITOR |
1oi9 |  | Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor |
1oiu |  | Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor |
1oiy |  | Structure of human Thr160-phospho CDK2/cyclin A complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor |
1okv |  | Cyclin A binding groove inhibitor H-Arg-Arg-Leu-Ile-Phe-NH2 |
1okw |  | Cyclin A binding groove inhibitor Ac-Arg-Arg-Leu-Asn-(m-Cl-Phe)-NH2 |
1ol1 |  | Cyclin A binding groove inhibitor H-Cit-Cit-Leu-Ile-(p-F-Phe)-NH2 |
1ol2 |  | Cyclin A binding groove inhibitor H-Arg-Arg-Leu-Asn-(p-F-Phe)-NH2 |
1p5e |  | The strucure of phospho-CDK2/cyclin A in complex with the inhibitor 4,5,6,7-tetrabromobenzotriazole (TBS) |
1pkd |  | THE CRYSTAL STRUCTURE OF UCN-01 IN COMPLEX WITH PHOSPHO-CDK2/CYCLIN A |
1qmz |  | PHOSPHORYLATED CDK2-CYCLYIN A-SUBSTRATE PEPTIDE COMPLEX |
1urc |  | Cyclin A binding groove inhibitor Ace-Arg-Lys-Leu-Phe-Gly |
1vin |  | BOVINE CYCLIN A3 |
1vyw |  | Structure of CDK2/Cyclin A with PNU-292137 |
1w98 |  | The structural basis of CDK2 activation by cyclin E |
2b9r |  | Crystal Structure of Human Cyclin B1 |
2bkz |  | STRUCTURE OF CDK2-CYCLIN A WITH PHA-404611 |
2bpm |  | STRUCTURE OF CDK2-CYCLIN A WITH PHA-630529 |
2c4g |  | STRUCTURE OF CDK2-CYCLIN A WITH PHA-533514 |
2c5n |  | Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design |
2c5o |  | Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design |
2c5v |  | Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design |
2c5x |  | Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design |
2c6t |  | Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor |
2cch |  | The crystal structure of CDK2 cyclin A in complex with a substrate peptide derived from CDC modified with a gamma-linked ATP analogue |
2cci |  | Crystal structure of phospho-CDK2 Cyclin A in complex with a peptide containing both the substrate and recruitment sites of CDC6 |
2cjm |  | Mechanism of CDK inhibition by active site phosphorylation: CDK2 Y15p T160p in complex with cyclin A structure |
2g9x |  | Structure of Thr 160 phosphorylated CDK2/cyclin A in complex with the inhibitor NU6271 |
2i40 |  | Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor |
2iw6 |  | STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR |
2iw8 |  | STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A F82H-L83V-H84D MUTANT WITH AN O6-CYCLOHEXYLMETHYLGUANINE INHIBITOR |
2iw9 |  | STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR |
2jgz |  | Crystal structure of phospho-CDK2 in complex with Cyclin B |
2uue |  | REPLACE: A strategy for Iterative Design of Cyclin Binding Groove Inhibitors |
2uzb |  | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor |
2uzd |  | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor |
2uze |  | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor |
2uzl |  | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor |
2v22 |  | REPLACE: A strategy for Iterative Design of Cyclin Binding Groove Inhibitors |
2w96 |  | Crystal Structure of CDK4 in complex with a D-type cyclin |
2w99 |  | Crystal Structure of CDK4 in complex with a D-type cyclin |
2w9f |  | Crystal Structure of CDK4 in complex with a D-type cyclin |
2w9z |  | Crystal Structure of CDK4 in complex with a D-type cyclin |
2wev |  | Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design |
2wfy |  | Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design |
2whb |  | Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design |
2wih |  | STRUCTURE OF CDK2-CYCLIN A WITH PHA-848125 |
2wip |  | STRUCTURE OF CDK2-CYCLIN A COMPLEXED WITH 8-ANILINO-1-METHYL-4,5-DIHYDRO- 1H-PYRAZOLO[4,3-H] QUINAZOLINE-3-CARBOXYLIC ACID |
2wma |  | Structural and thermodynamic consequences of cyclization of peptide ligands for the recruitment site of cyclin A |
2wmb |  | Structural and thermodynamic consequences of cyclization of peptide ligands for the recruitment site of cyclin A |
2wpa |  | Optimisation of 6,6-Dimethyl Pyrrolo 3,4-c pyrazoles: Identification of PHA-793887, a Potent CDK Inhibitor Suitable for Intravenous Dosing |
2wxv |  | Structure of CDK2-CYCLIN A with a Pyrazolo(4,3-h) quinazoline-3- carboxamide inhibitor |
2x1n |  | Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design |
3bht |  | Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 3 |
3bhu |  | Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 5 |
3bhv |  | Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor variolin B |
3ddp |  | Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor CR8 |
3ddq |  | Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor roscovitine |
3dog |  | Structure of Thr 160 phosphorylated CDK2/cyclin A in complex with the inhibitor N-&-N1 |
3eid |  | CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor |
3ej1 |  | CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor |
3eoc |  | Cdk2/CyclinA complexed with a imidazo triazin-2-amine |
3f5x |  | CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site |
3g33 |  | Crystal structure of CDK4/cyclin D3 |
3my5 |  | CDk2/cyclinA in complex with DRB |
3qhr |  | Structure of a pCDK2/CyclinA transition-state mimic |
3qhw |  | Structure of a pCDK2/CyclinA transition-state mimic |
3tnw |  | Structure of CDK2/cyclin A in complex with CAN508 |
4bck |  | Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor |
4bcm |  | Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor |
4bcn |  | Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor |
4bco |  | Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor |
4bcp |  | Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor |
4bcq |  | Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor |
4cfm |  | 4CFM |
4cfn |  | Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors. |
4cfu |  | 4CFU |
4cfv |  | 4CFV |
4cfw |  | Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors. |
4cfx |  | 4CFX |
4eoi |  | Thr 160 phosphorylated CDK2 K89D, Q131E - human cyclin A3 complex with the inhibitor RO3306 |
4eoj |  | Thr 160 phosphorylated CDK2 H84S, Q85M, K89D - human cyclin A3 complex with ATP |
4eok |  | Thr 160 phosphorylated CDK2 H84S, Q85M, K89D - human cyclin A3 complex with the inhibitor NU6102 |
4eol |  | Thr 160 phosphorylated CDK2 H84S, Q85M, K89D - human cyclin A3 complex with the inhibitor RO3306 |
4eom |  | Thr 160 phosphorylated CDK2 H84S, Q85M, Q131E - human cyclin A3 complex with ATP |
4eon |  | Thr 160 phosphorylated CDK2 H84S, Q85M, Q131E - human cyclin A3 complex with the inhibitor RO3306 |
4eoo |  | Thr 160 phosphorylated CDK2 Q131E - human cyclin A3 complex with ATP |
4eop |  | Thr 160 phosphorylated CDK2 Q131E - human cyclin A3 complex with the inhibitor RO3306 |
4eoq |  | Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with ATP |
4eor |  | Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with the inhibitor NU6102 |
4eos |  | Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with the inhibitor RO3306 |
4fx3 |  | Crystal Structure of the CDK2/Cyclin A complex with oxindole inhibitor |
4i3z |  | Structure of pCDK2/CyclinA bound to ADP and 2 Magnesium ions |
4ii5 |  | Structure of PCDK2/CYCLINA bound to ADP and 1 MAGNESIUM ION |
4y72 |  | 4Y72 |
4yc3 |  | 4YC3 |
5cyi |  | 5CYI |
5hq0 |  | 5HQ0 |
5if1 |  | 5IF1 |
5l2w |  | 5L2W |