The domain within your query sequence starts at position 193 and ends at position 359; the E-value for the EXOIII domain shown below is 3.34e-38.

All catalytic sites are present in this domain. Check the literature (PubMed 11937058 ) for details.



SMART accession number:SM00479
Description: exonuclease domain in DNA-polymerase alpha and epsilon chain, ribonuclease T and other exonucleases
Interpro abstract (IPR013520):

This entry includes a variety of exonuclease proteins, such as ribonuclease T [ (PUBMED:8506149) ] and the epsilon subunit of DNA polymerase III. Ribonuclease T is responsible for the end-turnover of tRNA,and removes the terminal AMP residue from uncharged tRNA. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria, and also exhibits 3' to 5' exonuclease activity.

Family alignment:
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There are 66161 EXOIII domains in 66129 proteins in SMART's nrdb database.

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