The domain within your query sequence starts at position 428 and ends at position 823; the E-value for the PBPe domain shown below is 4.11e-65.

HLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCID
ILKRLAHTIGFSYDLYLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIV
DFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPV
GYNRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFL
ASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSNYPDMH
SYMVRYNQPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYG
IALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSG

PBPe

Eukaryotic homologues of bacterial periplasmic substrate binding proteins.
PBPe
SMART accession number:SM00079
Description: Prokaryotic homologues are represented by a separate alignment: PBPb
Interpro abstract (IPR001320):

There are three classes of ionotropic glutamate receptors (iGluRs), namely NMDA (N-methyl-D-aspartate), AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole-4-propionic acid) and kainate receptors. They are believed to play critical roles in synaptic plasticity. At many synapses in the brain, transient activation of NMDA receptors leads to a persistent modification in the strength of synaptic transmission mediated by AMPA receptors and kainate receptors can act as the induction trigger for long-term changes in synaptic transmission [ (PUBMED:10580501) ].

Ionotropic glutamate receptors (iGluRs) are a highly conserved family of ligand-gated ion channels present in animals, plants, and bacteria, which are best characterised for their roles in synaptic communication in vertebrate nervous systems [ (PUBMED:14977400) ]. A variant subfamily of iGluRs, the Ionotropic Receptors (IRs), consist of non-glutamate-binding chemosensory receptors first identified in Drosophila melanogaster. They function in detecting odors and tastants [ (PUBMED:20808886) ].

GO component:membrane (GO:0016020)
GO function:ligand-gated ion channel activity (GO:0015276)
Family alignment:
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There are 11693 PBPe domains in 11580 proteins in SMART's nrdb database.

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