The domain within your query sequence starts at position 388 and ends at position 502; the E-value for the 4ae4 domain shown below is 1e-74.

LSPSERQCVETVVNMGYSYDCVLRAMRKKGENIEQILDYLFAHGQLCEKGFDPLLVEEAL
EMHQCSEEKMMEFLQLMSKFKEMGFELKDIKEVLLLHNNDQDNALEDLMARAGAS

This is a PDB domain - please see the PDBSUM entry of 4ae4 for further annotation