The domain within your query sequence starts at position 2265 and ends at position 2504; the E-value for the POLAc domain shown below is 3.3e-101.

All catalytic sites are present in this domain. Check the literature (PubMed 96353982 ) for details.



DNA polymerase A domain
SMART accession number:SM00482
Description: -
Interpro abstract (IPR001098):

Synonym(s): DNA nucleotidyltransferase (DNA-directed)

DNA-directed DNA polymerases( EC ) are the key enzymes catalysing the accurate replication of DNA. They require either a small RNA molecule or a protein as a primer for the de novo synthesis of a DNA chain. A number of polymerases belong to this family [ (PUBMED:2196557) (PUBMED:1870963) (PUBMED:8451181) ].

GO process:DNA replication (GO:0006260)
GO function:DNA binding (GO:0003677), DNA-directed DNA polymerase activity (GO:0003887)
Family alignment:
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There are 28198 POLAc domains in 28190 proteins in SMART's nrdb database.

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