SMART: Pfam domain AAA

The domain within your query sequence starts at position 336 and ends at position 603; the E-value for the AAA_8 domain shown below is 3.9e-166.

HNEVNAVMDLVLFEDAIRHICHINRILESPRGNALLVGVGGSGKQSLTKLAAFISSMDVF
QITLRKGYQIPDFKVDLASLCLKAGVKNLSTVFLMTDAHVADERFLVLINDLLASGEIPD
LYSDEEEENIINNVRNEVKSQGLMDSRENCWKFFIERVQRQLKVTLCFSPVGNKLRIRSR
KFPAIVNCTAINWFHEWPQEALESVSLRFLQNTKNIEPAVKQSISKFMAFVHISVNKTSQ
SYLTNEQRYNYTTPKSFLEFIRLYQSLL

AAA_8

PFAM accession number:	PF12780
Interpro abstract (IPR024317):	The 380kDa motor unit of dynein belongs to the AAA class of chaperone-like ATPases. The core of the 380kDa motor unit contains a concatenated chain of six AAA modules, of which four (D1 - D4) correspond to the ATP binding sites with P-loop signatures described previously, and two (D5, D6) are modules in which the P loop has been lost in evolution. This particular entry represents the D4 ATP-binding domain of the motor [ (PUBMED:11250194) ].

PFAM accession number:

PF12780

Interpro abstract (IPR024317):

The 380kDa motor unit of dynein belongs to the AAA class of chaperone-like ATPases. The core of the 380kDa motor unit contains a concatenated chain of six AAA modules, of which four (D1 - D4) correspond to the ATP binding sites with P-loop signatures described previously, and two (D5, D6) are modules in which the P loop has been lost in evolution. This particular entry represents the D4 ATP-binding domain of the motor [ (PUBMED:11250194) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry AAA_8