The domain within your query sequence starts at position 305 and ends at position 484; the E-value for the AKAP7_NLS domain shown below is 2.5e-24.
PTHFVALMVTESGLRAEVVKAQEHLVRIAPSCAEFLVPAQALHLTVVLLRLTGPGEEAAA ARALRRAILKPGLQAPSQLQFRDLVLLGHHVLCATPSPTLTGMAQTLNQRLEAEGLRVVL LPELQPHLTLAKVPHGTQVCLPKPEYTLNQELGRQPLSKLWLCRMGRAGHSYLPLVEISL
AKAP7_NLS |
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PFAM accession number: | PF10469 |
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Interpro abstract (IPR019510): | This entry represents the nuclear localisation signal-containing domain found in the cyclic AMP-dependent protein kinase A (PKA) anchor protein, AKAP7. This protein anchors PKA for its role in regulating PKA-mediated gene transcription in both somatic cells and oocytes [ (PUBMED:12804576) ]. This domain carries the nuclear localisation signal (NLS) KKRKK, that indicates the cellular destiny of this anchor protein [ (PUBMED:16483255) ]. The domain is also found in a number of other proteins, such as activating signal cointegrator 1 complex subunit 1 and leukocyte receptor cluster member 9. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry AKAP7_NLS