SMART: Pfam domain AKNA

The domain within your query sequence starts at position 584 and ends at position 681; the E-value for the AKNA domain shown below is 4.6e-37.

LEQLRAAHMALEAEYLQACREELLDPQLDASQGSPRTLNLCRELEAEIYHLGQRLEELQD
HMDQTQRETEPCRPDLQDSTPTMSFLPQSAHLSMPSGP

AKNA

PFAM accession number:	PF12443
Interpro abstract (IPR022150):	This domain can be found in microtubule organization protein AKNA (also known as AT-hook-containing transcription factor) in eukaryotes, and is approximately 110 amino acids in length. AKNA which regulates the expression of the costimulatory molecules on lymphocytes and lays a key role in cell delamination by regulating the microtubule organization [ (PUBMED:30787442) ]. This domain can also be found in AKNAD1 (AKNA Domain Containing 1). It has been linked to type-2 diabetes [ (PUBMED:26292654) ].

PFAM accession number:

PF12443

Interpro abstract (IPR022150):

This domain can be found in microtubule organization protein AKNA (also known as AT-hook-containing transcription factor) in eukaryotes, and is approximately 110 amino acids in length. AKNA which regulates the expression of the costimulatory molecules on lymphocytes and lays a key role in cell delamination by regulating the microtubule organization [ (PUBMED:30787442) ].

This domain can also be found in AKNAD1 (AKNA Domain Containing 1). It has been linked to type-2 diabetes [ (PUBMED:26292654) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry AKNA