The domain within your query sequence starts at position 21 and ends at position 115; the E-value for the ANAPC15 domain shown below is 9.5e-44.



PFAM accession number:PF15243
Interpro abstract (IPR026182):

Human ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C; it is not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It also required for degradation of CDC20 [ (PUBMED:21926987) ].

GO process:regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)
GO component:anaphase-promoting complex (GO:0005680)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry ANAPC15