The domain within your query sequence starts at position 232 and ends at position 431; the E-value for the ANAPC4 domain shown below is 3.7e-61.



PFAM accession number:PF12896
Interpro abstract (IPR024790):

Apc4 is one of the larger of the subunits of the anaphase-promoting complex (APC) or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes [ (PUBMED:12049731) (PUBMED:16896351) ]. Results in Caenorhabditis elegans show that the primary essential role of the spindle assembly checkpoint is not in the chromosome segregation process itself but rather in delaying anaphase onset until all chromosomes are properly attached to the spindle. The APC is likely to be required for all metaphase-to-anaphase transitions in a multicellular organism [ (PUBMED:10749938) ].

This entry represents the long domain downstream of the WD40 repeat/s that are present on the Apc4 subunits.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry ANAPC4