The domain within your query sequence starts at position 35 and ends at position 105; the E-value for the Alba domain shown below is 3.3e-16.
NDIYVNMKTDFKAQLARCQKLLDGGTRGQNACTEIYIHGLGLAINRAINIALQLQAGSFG SLQVAANTSTV
Alba |
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PFAM accession number: | PF01918 |
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Interpro abstract (IPR002775): | Members of this group include the archaeal protein Alba and eukaryotic Ribonuclease P subunits Pop7/Rpp20 and Rpp25. The Alba domain is closely related to the RNA-binding versions of the IF3-C fold such as YhbY and IF3-C. The eukaryotic lineages of the Alba family are principally involved in RNA metabolism, suggesting that the ancestral function of the IF3-C fold was related to RNA interaction [ (PUBMED:14519199) ]. Alba has been shown to bind DNA and affect DNA supercoiling in a temperature dependent manner [ (PUBMED:10869069) ]. It is regulated by acetylation (alba = acetylation lowers binding affinity) by the Sir2 protein. Alba is proposed to play a role in establishment or maintenance of chromatin architecture and thereby in transcription repression. For further information see [ (PUBMED:16256418) ]. |
GO function: | nucleic acid binding (GO:0003676) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Alba