The domain within your query sequence starts at position 1 and ends at position 143; the E-value for the Amidohydro_1 domain shown below is 3.6e-10.



PFAM accession number:PF01979
Interpro abstract (IPR006680):

Proteins containing this domain are enzymes from a large metal dependent hydrolase superfamily [ (PUBMED:9144792) ]. The family includes adenine deaminase ( EC ) that hydrolyses adenine to form hypoxanthine and ammonia. This reaction is important for adenine utilisation as a purine and also as a nitrogen source [ (PUBMED:8550522) ]. The family also includes dihydroorotase and N-acetylglucosamine-6-phosphate deacetylases ( EC ). The domain is also found in the urease alpha subunit, where it is the catalytic domain [ (PUBMED:7754395) ].

GO function:hydrolase activity (GO:0016787)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Amidohydro_1