The domain within your query sequence starts at position 54 and ends at position 144; the E-value for the BST2 domain shown below is 1.9e-37.



PFAM accession number:PF16716
Interpro abstract (IPR024886):

Bone marrow stromal antigen 2, also known as tetherin, is an antiretroviral defence protein, that blocks release of enveloped virus from the cell surface [ (PUBMED:18200009) (PUBMED:20686043) (PUBMED:20940320) ]. Bst2/tetherin contains two membrane anchors which are employed to retain some enveloped viruses, including HIV-1, tethered to the plasma membrane in the absence of virus encoded antagonists [ (PUBMED:20399176) ]. Its expression is induced by interferon-alpha [ (PUBMED:19032371) ] and was originally linked to B cell development [ (PUBMED:7607676) ].

GO process:defense response to virus (GO:0051607)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry BST2