SMART: Pfam domain CEP170

The domain within your query sequence starts at position 204 and ends at position 598; the E-value for the CEP170_C domain shown below is 8.9e-174.

ELDSCRAPAEPPDYSFRREPSYFEIPTKETPQPPRLPEVPTQEVPTKDQEAGVGGTAPAR
TGFSGRSAELYSTSRKPTIAEARAAAKKAAATAANTGPRQPFSRARPGSARYSSNTRRRQ
QGSDYTSTSEEEYGSHHSSPKHTRSHASTATQTPRGSSSTRARSQGPRDTDDDEEEPDPY
GFIVQTAEIAEIARLSQTLVKDVAILAREIHDVAGDGDSLGSPGPTRSPSLGNVPNTPAS
TISAREELVQRIPEASLNFQKVPPGSMNSHNLDQNMNDSRDDALTNKTRPRNREEVIFDN
LMLNPVSQLSHAIRENTEHLAEKMKVLFQNTGRAWEDLEARINSENEVPILKTSNKEISS
ILKELRRVQKQLEVINAIVDPSLNLDLLMGNRAPS

CEP170_C

PFAM accession number:	PF15308
Interpro abstract (IPR029300):	This entry represents the C terminus of centrosomal protein of 170kDa (CEP170) [ (PUBMED:15616186) ]. Centrosomal protein of 170kDa (Cep170) plays a role in microtubule organisation [ (PUBMED:15616186) ]. Human Cep170 is constantly expressed throughout the cell cycle, but phosphorylated during mitosis. Cep170 is a substrate of Polo-like kinase 1 (Plk1) [ (PUBMED:15616186) ]. It is associated with the mature mother centriole. Cep170 is also required for Kif2b-induced microtubule depolymerisation [ (PUBMED:23087211) ].

PFAM accession number:

PF15308

Interpro abstract (IPR029300):

This entry represents the C terminus of centrosomal protein of 170kDa (CEP170) [ (PUBMED:15616186) ].

Centrosomal protein of 170kDa (Cep170) plays a role in microtubule organisation [ (PUBMED:15616186) ]. Human Cep170 is constantly expressed throughout the cell cycle, but phosphorylated during mitosis. Cep170 is a substrate of Polo-like kinase 1 (Plk1) [ (PUBMED:15616186) ]. It is associated with the mature mother centriole. Cep170 is also required for Kif2b-induced microtubule depolymerisation [ (PUBMED:23087211) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry CEP170_C