The domain within your query sequence starts at position 242 and ends at position 755; the E-value for the CHGN domain shown below is 1.7e-144.

HLDGCRGDILSARPDEWLGRCLIDTLGIGCVSQHQGQQYRSFELAKNRDPEKEESPAFLS
AFAVHPVPEGTLMYRLHKRFSALELERAYSEIEQLQAQIRNLTVLTPEGEAGLSWPVGLP
APFTPHSRFEVLGWDYFTEQHTFACADGAPKCPLQGASRADVGDAVDTALEQLNRRYQPR
LRFRKQRLLNGYRRFDPARGMEYTLDLLLEAVTQRGHRRSLARRVSLLRPLSRVEILPMP
YVTEATRVQLVLPLLVAEAPAALAFLEAFAASVLEPREHALLTLLLVYGPREGRGGPDPF
LGVKAAAAELERRYPGARLAWLAVRAEAPSQVRLMDVISKKHPVDTLFFLTTVWTRPGSE
VLNRCRMNAISGWQAFFPVHFQEFNPALSPQRSPPGVPGADPPSPGVDPSRGAPVGGRFD
RQASAEGCFYNADYLAARARLAGELAGQEEEEALEGLEVMDVFLRFSGLHLFRAVEPGLV
QKFSLRDCSPRLSEELYHRCRLSNLEGLGARTQL

CHGN

CHGN
PFAM accession number:PF05679
Interpro abstract (IPR008428):

This family represents Chondroitin N-acetylgalactosaminyltransferase. Proteins have a type II transmembrane topology. The enzyme is involved in the biosynthetic initiation and elongation of chondroitin sulphate and is the key enzyme responsible for the selective chain assembly of chondroitin/dermatan sulphate on the linkage region tetrasaccharide common to various proteoglycans containing chondroitin/dermatan sulphate or heparin/heparan sulphate chains [ (PUBMED:11788602) (PUBMED:11514575) ].

GO component:Golgi cisterna membrane (GO:0032580)
GO function:acetylgalactosaminyltransferase activity (GO:0008376)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry CHGN