The domain within your query sequence starts at position 35 and ends at position 158; the E-value for the COG5 domain shown below is 3.8e-37.
SEFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIE SLEGVLQMMQTRIGALQGAVDRMKSKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYL SKRL
COG5 |
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PFAM accession number: | PF10392 |
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Interpro abstract (IPR019465): | The conserved oligomeric Golgi (COG) complex is a peripheral membrane complex involved in intra-Golgi protein trafficking. Subunit 5 is located in the smaller, B lobe, together with subunits 6-8, and has been shown to bind subunits 1 and 7 [ (PUBMED:15932880) ]. Defects in COG5 are the cause of congenital disorder of glycosylation type 2I (CDG2I). A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterised by under-glycosylated serum glycoproteins [ (PUBMED:19690088) ]. |
GO process: | intra-Golgi vesicle-mediated transport (GO:0006891) |
GO component: | Golgi transport complex (GO:0017119) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry COG5