The domain within your query sequence starts at position 144 and ends at position 183; the E-value for the CUE domain shown below is 4.6e-7.



PFAM accession number:PF02845
Interpro abstract (IPR003892):

This domain promotes intramolecular monoubiquitination and has a dual role in mono- and poly-ubiquitination recognition, being involved in binding ubiquitin-conjugating enzymes (UBCs) [ (PUBMED:12573224) (PUBMED:12628920) (PUBMED:23665229) ]. CUE domains also occur in two proteins of the IL-1 signal transduction pathway, tollip and TAB2.

GO function:protein binding (GO:0005515)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry CUE