The domain within your query sequence starts at position 12 and ends at position 264; the E-value for the Ceramidase domain shown below is 5.4e-58.

SIFAYQSSEVDWCESNFQHSELVAEFYNTFSNVFFLIFGPLMMFLMHPYAQKRTRCFYGV
SVLFMLIGLFSMYFHMTLSFLGQLLDEISILWLLASGYSVWLPRCYFPKFVKGNRFYFSC
LVTITTIISTFLTFVKPTVNAYALNSIAIHILYIVRTEYKKIRDDDLRHLIAVSVVLWAA
ALTSWISDRVLCSFWQRIHFYYLHSIWHVLISITFPYGIVTMALVDAKYEMPDKTLKVHY
WPRDSWVIGLPYV

Ceramidase

Ceramidase
PFAM accession number:PF05875
Interpro abstract (IPR008901):

This entry consists of several ceramidases. Ceramidases are enzymes involved in regulating cellular levels of ceramides, sphingoid bases, and their phosphates [ (PUBMED:11356846) ].

GO process:ceramide metabolic process (GO:0006672)
GO component:integral component of membrane (GO:0016021)
GO function:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Ceramidase