The domain within your query sequence starts at position 52 and ends at position 388; the E-value for the CiPC domain shown below is 6.6e-107.
SDKDSGFSDGSSECLSSAEQMESEDMLSALGCKREDKRRQPSKAADTALPTLPPMVVMKS VLVKQGSSSSQLQSWTVQPSFEVISAQPQLFVLHPPVPSPVSSCQTGEKKSESRNYLPIL NSYTKIAPHPGKRGLNSEDRGTSGVSKKLCTERPGPSLSSSEPAKTGRVLSSPSTPAPPS SKLTEDSTLQGVPSLGAGGSPQTLQPVSSSHVAKAPSLTLASPASPVCASDSTLHGLESS SPLSPLSASYTSPLWAAEHLCRSPDIFSEQRQNKHRRFQNTLVVLHKSGLLEITLKTKEL IRQNQATQAELDQLKEQTQMFIEATKSRAPQAWAKLQ
CiPC |
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PFAM accession number: | PF15800 |
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Interpro abstract (IPR031602): | Clock-interacting pacemaker or clock-interacting circadian protein (CIPC) is an additional negative-feedback regulator of the circadian clock, through inhibition of CLOCK-BMAL1 activity [ (PUBMED:17310242) (PUBMED:19414601) (PUBMED:19341811) ]. Studies in knockout mice suggest that it may not be critically required for basic clock function [ (PUBMED:25862660) ]. |
GO process: | negative regulation of transcription, DNA-templated (GO:0045892), negative regulation of circadian rhythm (GO:0042754) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry CiPC