The domain within your query sequence starts at position 18 and ends at position 197; the E-value for the Claudin_2 domain shown below is 2.5e-23.

ACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEY
FLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIF
FILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSV

Claudin_2

PFAM accession number:

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Claudin_2