The domain within your query sequence starts at position 196 and ends at position 250; the E-value for the Crisp domain shown below is 6.2e-25.



PFAM accession number:PF08562
Interpro abstract (IPR013871):

This entry is found on Crisp proteins which contain IPR001283 and has been termed the Crisp domain. It is found in the mammalian reproductive tract and the venom of reptiles, and has been shown to regulate ryanodine receptor Ca2+ signalling [ (PUBMED:16339766) ]. It contains 10 conserved cysteines which are all involved in disulphide bonds and is structurally related to the ion channel inhibitor toxins BgK and ShK [ (PUBMED:16339766) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Crisp