The domain within your query sequence starts at position 57 and ends at position 156; the E-value for the DHDPS domain shown below is 5.8e-11.
RLATFPFRGAVGGICGLANVLGAQVCQLERLCLTGQWEAAQELQHRLIEPNTAVTRRFGI PGLKKTMDWFGYYGGPCRAPLQELSPTEEEALRLDFSNNG
DHDPS |
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PFAM accession number: | PF00701 |
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Interpro abstract (IPR002220): | Dihydrodipicolinate synthase (EC 4.2.1.52) (DHDPS, DapA) catalyses, in higher plants, some fungi and bacteria (gene dapA), the first reaction specific to the biosynthesis of lysine and of diaminopimelate [ (PUBMED:22949190) ]. DHDPS is responsible for the condensation of aspartate semialdehyde and pyruvate by a ping-pong mechanism in which pyruvate first binds to the enzyme by forming a Schiff-base with a lysine residue [ (PUBMED:1463470) (PUBMED:20025926) ]. Other proteins are structurally related to DHDPS and probably also act via a similar catalytic mechanism [ (PUBMED:9047371) ]:
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GO function: | lyase activity (GO:0016829) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry DHDPS